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Articles (35)

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1-10 of 35 results for physiologically based pharmacokinetic (PBPK) model

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Select article: Toxicokinetic Model Development for the Insensitive Munitions Component 2,4-Dinitroanisole

Free access

Research article

First published 2015-9

Toxicokinetic Model Development for the Insensitive Munitions Component 2,4-Dinitroanisole

Lisa M. Sweeney, Michelle R. Goodwin, Angela D. Hulgan [...]

International Journal of Toxicology

Select article: Physiologically-based Pharmacokinetic Modelling for the Reduction of Animal Use in the Discovery of Novel Pharmaceuticals

Retricted access

Research article

First published 2010-12

Physiologically-based Pharmacokinetic Modelling for the Reduction of Animal Use in the Discovery of Novel Pharmaceuticals

Simon Thomas

Alternatives to Laboratory Animals

Select article: A Physiologically Based Pharmacokinetic Model of Parathion Based on Chemical-Specific Parameters Determined In Vitro

Free access

Research article

First published 1990-11

A Physiologically Based Pharmacokinetic Model of Parathion Based on Chemical-Specific Parameters Determined In Vitro

Lester G. Sultatos

International Journal of Toxicology

Select article: Physiologically based pharmacokinetic modeling to predict the effect of risperidone on aripiprazole pharmacokinetics in subjects with different CYP2D6 genotypes and individuals with hepatic impairment

Open access

Research article

First published 2024

Physiologically based pharmacokinetic modeling to predict the effect of risperidone on aripiprazole pharmacokinetics in subjects with different CYP2D6 genotypes and individuals with hepatic impairment

Fan Mou, Zhiwei Huang, Yu Cheng [...]

Therapeutic Advances in Drug Safety

Select article: An Approach for Incorporating Tissue Composition Data Into Physiologically Based Pharmacokinetic Models

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Research article

First published 1995-09

An Approach for Incorporating Tissue Composition Data Into Physiologically Based Pharmacokinetic Models

Michael Pelekis, Patrick Poulin, Kannan Krishnan

Toxicology and Industrial Health

Select article: Application of Physiologically Based Pharmacokinetic Modeling of Lamotrigine Using PK-Sim in Predicting the Impact of Drug Interactions and Dosage Adjustment

Open access

Research article

First published 2022-6

Application of Physiologically Based Pharmacokinetic Modeling of Lamotrigine Using PK-Sim in Predicting the Impact of Drug Interactions and Dosage Adjustment

Mohammed Farhan, Prathvi Rani, Fatimazahra Moledina [...]

Journal of Pharmacology and Pharmacotherapeutics

Select article: Development of Physiologically Based Pharmacokinetic Model and Assessment of the Impact of Renal Underdevelopment in Preterm Infants on the Pharmacokinetics of Aminophylline

Open access

Research article

First published 2022-3

Development of Physiologically Based Pharmacokinetic Model and Assessment of the Impact of Renal Underdevelopment in Preterm Infants on the Pharmacokinetics of Aminophylline

Hari Prabhath Tummala, Rachana Balusu, Sahithi Thotakura [...]

Journal of Pharmacology and Pharmacotherapeutics

Select article: Silver Diamine Fluoride in Children Using Physiologically Based PK Modeling

Retricted access

Research article

First published 2020-7

Silver Diamine Fluoride in Children Using Physiologically Based PK Modeling

K.-F. Chen, P. Milgrom, Y.S. Lin

Journal of Dental Research

Select article: A Simple Index for Representing the Discrepancy between Simulations of Physiological Pharmacokinetic Models and Experimental Data

Retricted access

Research article

First published 1995-07

A Simple Index for Representing the Discrepancy between Simulations of Physiological Pharmacokinetic Models and Experimental Data

Kannan Krishnan, Sami Haddad, Michael Pelekis

Toxicology and Industrial Health

Select article: Application of in vitro biotransformation data and pharmacokinetic modeling to risk assessment

Retricted access

Research article

First published 2001-6

Application of in vitro biotransformation data and pharmacokinetic modeling to risk assessment

Gregory L Kedderis, John C Lipscomb

Toxicology and Industrial Health

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