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Research article

First published 2024-12

A Pathologist’s Guide to Non-clinical Safety Assessment of Adoptive Cell Therapy Products

Alessandra Piersigilli, Vinicius S. Carreira, Frédéric Gervais [...]

Toxicologic Pathology

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Research article

First published 2009-11

The Use of Computer Models in Pharmaceutical Safety Evaluation

Scott Boyer

Alternatives to Laboratory Animals

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Research article

First published 2013-2

On-target and Off-target-based Toxicologic Effects

Daniel G. Rudmann

Toxicologic Pathology

Open access

Review article

First published 2018-2

T-cell Immunotherapies and the Role of Nonclinical Assessment: The Balance between Efficacy and Pathology

Michaela E. Sharpe

Toxicologic Pathology

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Research article

First published 2025-6

Dose selection criteria to identify the optimal dose based on ranked efficacy-toxicity outcomes without reliance on clinical utilities

Sydney Porter, Anne Eaton, Thomas A Murray

Statistical Methods in Medical Research

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Research article

First published 2015-1

Antisense Oligonucleotide Therapies

Kendall S. Frazier

Toxicologic Pathology

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Research article

First published 2015-06

211 Astatine-Conjugated Monoclonal CD45 Antibody-Based Nonmyeloablative Conditioning for Stem Cell Gene Therapy

Christopher R. Burtner, Devikha Chandrasekaran, Erlinda B. Santos [...]

Human Gene Therapy

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Research article

First published 2018-10

Role of Computationally Evaluated Target Specificity in the Hepatotoxicity of Gapmer Antisense Oligonucleotides

Takeshi Kasuya, Akira Kugimiya

Nucleic Acid Therapeutics

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Research article

First published 2014-12

Effective sample size for computing prior hyperparameters in Bayesian phase I–II dose-finding

Peter F Thall, Richard C Herrick, Hoang Q Nguyen [...]

Clinical Trials

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Review article

First published 2015-11

Targeting Head and Neck Cancer Stem Cells

A.C. Birkeland, J.H. Owen, M.E. Prince

Journal of Dental Research

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