Sage Journals: Discover world-class research

Retricted access

Research article

First published 2004-03

Modulation of CpG Oligodeoxynucleotide-Mediated Immune Stimulation by Locked Nucleic Acid (LNA)

Jörg Vollmer, Jan Stenvang Jepsen, Eugen Uhlmann [...]

Nucleic Acid Therapeutics

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Research article

First published 2004-04

Downregulation of p21 (WAF1/CIP1) and Estrogen Receptor α in MCF-7 Cells by Antisense Oligonucleotides Containing Locked Nucleic Acid (LNA)

Jan Stenvang Jepsen, Henrik M. Pfundheller, Anne E. Lykkesfeldt

Nucleic Acid Therapeutics

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Research article

First published 2003-12

A Structure-Activity Study of the Inhibition of HIV-1 Tat-Dependent Trans- Activation by Mixmer 2′- O -Methyl Oligoribonucleotides Containing Locked Nucleic Acid (LNA),α -L-LNA,or 2′-Thio-LNA Residues

Andrey Arzumanov, Dmitry A. Stetsenko, Andrey D. Malakhov [...]

Nucleic Acid Therapeutics

Free access

Research article

First published 2010-3

LNA-based PCR clamping enrichment assay for the identification of KRAS mutations

Edna Efrati, Hela Elkin, Yehudit Peerless [...]

Cancer Biomarkers

Free access

Research article

First published 2021-8

Safety,Tissue Distribution,and Metabolism of LNA-Containing Antisense Oligonucleotides in Rats

Fernando Romero-Palomo, Matthias Festag, Barbara Lenz [...]

Toxicologic Pathology

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Review article

First published 2004-04

Locked Nucleic Acid: A Potent Nucleic Acid Analog in Therapeutics and Biotechnology

Jan Stenvang Jepsen, Mads D. S⊘rensen, Jesper Wengel

Nucleic Acid Therapeutics

Free access

Research article

First published 2001-8

Multiplex SNP Genotyping Using Locked Nucleic Acid and Microfluidics

Yoanna Choleva, Mikkel Nørholm, Susanne Pedersen [...]

Journal of Laboratory Automation

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Research article

First published 2022-06

Altered Biodistribution and Hepatic Safety Profile of a Gapmer Antisense Oligonucleotide Bearing Guanidine-Bridged Nucleic Acids

Takashi Sasaki, Yoko Hirakawa, Fumiko Yamairi [...]

Nucleic Acid Therapeutics

Open access

Brief report

First published 2012-10

Internalization of Locked Nucleic Acids/DNA Hybrid Oligomers into Escherichia coli

German M. Traglia, Carol Davies Sala, Juan I. Fuxman Bass [...]

BioResearch Open Access

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Research article

First published 2009-03

Noncovalent Peptide-Mediated Delivery of Chemically Modified Steric Block Oligonucleotides Promotes Splice Correction: Quantitative Analysis of Uptake and Biological Effect

Sandra D. Laufer, Anna Lena Recke, Sandra Veldhoen [...]

Nucleic Acid Therapeutics

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