Sage Journals: Discover world-class research

Open access

Review article

First published 2022

Huntingtin and Its Partner Huntingtin-Associated Protein 40: Structural and Functional Considerations in Health and Disease

Manuel Seefelder, Fabrice A.C. Klein, Bernhard Landwehrmeyer [...]

Journal of Huntington's Disease

Open access

Research article

First published 2025-11

Dysregulation of huntingtin interacting protein networks in human juvenile Huntington's disease brain

Sonia Podvin, Brin Rosenthal, Charles Mosier [...]

Journal of Huntington's Disease

Open access

Research article

First published 2025-08

Intrastriatal Delivery of a Zinc Finger Protein Targeting the Mutant HTT Gene Allele Obviates Lipid Phenotypes in Brain and Plasma in Huntington's Disease Mice

Andrew Iwanowicz, Adel Boudi, Connor Seeley [...]

Human Gene Therapy

Retricted access

Research article

First published 2024-08

mRNA Nuclear Clustering Leads to a Difference in Mutant Huntingtin mRNA and Protein Silencing by siRNAs In Vivo

Sarah Allen, Daniel O’reilly, Rachael Miller [...]

Nucleic Acid Therapeutics

Retricted access

Research article

First published 2014-8

Huntingtin Supplies a csaA-Independent Function Essential for EDTA-Resistant Homotypic Cell Adhesion in Dictyostelium discoideum

Morgan N. Thompson, Marcy E. MacDonald, James F. Gusella [...]

Journal of Huntington's Disease

Retricted access

Research article

First published 2014-02

Preventing Formation of Toxic N-Terminal Huntingtin Fragments Through Antisense Oligonucleotide-Mediated Protein Modification

Melvin M. Evers, Hoang-Dai Tran, Ioannis Zalachoras [...]

Nucleic Acid Therapeutics

Open access

Review article

First published 2018

Cancer: From Wild-Type to Mutant Huntingtin

Morgane Sonia Thion, Sandrine Humbert

Journal of Huntington's Disease

Retricted access

Research article

First published 2019-10

Lowering Mutant Huntingtin Using Tricyclo-DNA Antisense Oligonucleotides As a Therapeutic Approach for Huntington's Disease

Marine Imbert, Florence Blandel, Christian Leumann [...]

Nucleic Acid Therapeutics

Open access

Review article

First published 2013-5

Degradation of Misfolded Proteins by Autophagy: Is it a Strategy for Huntington's Disease Treatment?

Fang Lin, Zheng-Hong Qin

Journal of Huntington's Disease

Open access

Review article

First published 2024-09-10

Protective Proteolysis in Huntington’s Disease: Unraveling the Role of Post-Translational Myristoylation of Huntingtin in Autophagy

Yasmeen Alshehabi, Dale D.O. Martin

Journal of Huntington's Disease

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