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Articles (32)

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1-10 of 32 results for human ether-a-go-go related gene (hERG)

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Select article: Blockade of Human Ether-A-Go-Go Related Gene (Herg) Channels by Quinidine

Retricted access

Research article

First published 2004-3

Blockade of Human Ether-A-Go-Go Related Gene (Herg) Channels by Quinidine

L. Congrong, I. Cvetanovic, V. Ranade [...]

Journal of Investigative Medicine

Select article: Cellular mechanisms for trazodone-induced cardiotoxicity

Free access

Research article

First published 2016-5

Cellular mechanisms for trazodone-induced cardiotoxicity

S Lee, H-A Lee, SJ Kim [...]

Human & Experimental Toxicology

Select article: Electrophysiological safety of DW-286a,a novel fluoroquinolone antibiotic agent

Free access

Research article

First published 2005-01

Electrophysiological safety of DW-286a,a novel fluoroquinolone antibiotic agent

Eun-Joo Kim, Ki-Suk Kim, Won-Ho Shin

Human & Experimental Toxicology

Select article: Utility of hERG Assays as Surrogate Markers of Delayed Cardiac Repolarization and QT Safety

Free access

Research article

First published 2006-1

Utility of hERG Assays as Surrogate Markers of Delayed Cardiac Repolarization and QT Safety

Gary A. Gintant, Zhi Su, Ruth L. Martin [...]

Toxicologic Pathology

Select article: Improved Throughput of PatchXpress hERG Assay Using Intracellular Potassium Fluoride

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Research article

First published 2008-04

Improved Throughput of PatchXpress hERG Assay Using Intracellular Potassium Fluoride

Haoyu Zeng, Jacob R. Penniman, Fumi Kinose [...]

ASSAY and Drug Development Technologies

Select article: Using Electrophysiology and In Silico Three-Dimensional Modeling to Reduce Human Ether-à-go-go Related Gene K + Channel Inhibition in a Histamine H3 Receptor Antagonist Program

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Research article

First published 2010-12

Using Electrophysiology and In Silico Three-Dimensional Modeling to Reduce Human Ether-à-go-go Related Gene K + Channel Inhibition in a Histamine H3 Receptor Antagonist Program

Adam J. Davenport, Clemens Möller, Alexander Heifetz [...]

ASSAY and Drug Development Technologies

Select article: Automated Tight Seal Electrophysiology for Assessing the Potential hERG Liability of Pharmaceutical Compounds

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Research article

First published 2004-10

Automated Tight Seal Electrophysiology for Assessing the Potential hERG Liability of Pharmaceutical Compounds

Huimin Tao, David Santa Ana, António Guia [...]

ASSAY and Drug Development Technologies

Select article: Clenbuterol Attenuates hERG Channel by Promoting the Mature Channel Degradation

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Research article

First published 2017-7

Clenbuterol Attenuates hERG Channel by Promoting the Mature Channel Degradation

Ling Luo, Peijing Hu, Changqing Miao [...]

International Journal of Toxicology

Select article: Development of Recombinant Cell Line Co-expressing Mutated Nav1.5,Kir2.1,and hERG for the Safety Assay of Drug Candidates

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Research article

First published 2012-7

Development of Recombinant Cell Line Co-expressing Mutated Nav1.5,Kir2.1,and hERG for the Safety Assay of Drug Candidates

Masato Fujii, Susumu Ohya, Hisao Yamamura [...]

Journal of Biomolecular Screening

Select article: Time Is a Critical Factor When Evaluating Oligonucleotide Therapeutics in hERG Assays

Open access

Research article

First published 2023-04

Time Is a Critical Factor When Evaluating Oligonucleotide Therapeutics in hERG Assays

Yusheng Qu, Robert Kirby, Richard Davies [...]

Nucleic Acid Therapeutics

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