Sage Journals: Discover world-class research

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Brief report

First published 2023-8

Can Historical Control Group Data Be Used to Replace Concurrent Controls in Animal Studies?

Thomas Steger-Hartmann, Matthew Clark

Toxicologic Pathology

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Research article

First published 2003-10

Evaluation of historical control data in carcinogenicity studies

H Greim, H-P Gelbke, U Reuter [...]

Human & Experimental Toxicology

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Research article

First published 2022-7

The Influence of Geographical Origin,Age,Sex,and Animal Husbandry on the Spontaneous Histopathology of Laboratory Cynomolgus Macaques ( Macaca Fascicularis ): A Contemporary Global and Multisite Review of Historical Control Data

Ronnie Chamanza, Stuart W. Naylor, Michela Gregori [...]

Toxicologic Pathology

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Research article

First published 2025-2

IHI VICT3R: Developing and Implementing Virtual Control Groups to Reduce Animal Use in Toxicology Research

Thomas Steger-Hartmann, Ferran Sanz, Frank Bringezu [...]

Toxicologic Pathology

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Research article

First published 1983-01

Statistical Issues in the Design and Analysis of Carcinogenicity Bioassays

Gerald Hajian

Toxicologic Pathology

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Research article

First published 2002-01

The Value of Historical Control Data—Scientific Advantages for Pathologists,Industry and Agencies

Ulrich Deschl, Birgit Kittel, Susanne Rittinghausen [...]

Toxicologic Pathology

Retricted access

Research article

First published 2016-3

Community Opinions on the Collection and Use of Historical Control Data in Nonclinical Toxicity Studies

Lauren Murphree Mihalcik, Megan Bausman, Paul Brown [...]

Therapeutic Innovation & Regulatory Science

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Research article

First published 1991-5

The Need for a Control Animal Pathology Database: An International Survey

J.A.N. McAuslane, C.E. Lumley, S.R. Walker

Human & Experimental Toxicology

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Research article

First published 2018-6

High Background Incidence of Spontaneous Subcapsular Adrenal Gland Hyperplasia of Tg.rasH2 Mice Used in 26-week Carcinogenicity Studies

Molly H. Boyle, Madhav G. Paranjpe, Dianne M. Creasy

Toxicologic Pathology

Retricted access

Research article

First published 1992-4

Value of Historical Controls in the Interpretation of Rodent Tumor Data

J. K. Haseman

Therapeutic Innovation & Regulatory Science

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