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Review article

First published 2025-8

Biased Agonism in Incretin-based Therapies

Krishna G. Seshadri

International Journal of Clinical Metabolism and Diabetes

Open access

Research article

First published 2014-1

β-Arrestin-2-Biased Agonism of Delta Opioid Receptors Sensitizes Transient Receptor Potential Vanilloid Type 1 (TRPV1) in Primary Sensory Neurons

Matthew P Rowan, Kalina Szteyn, Allison P Doyle [...]

Molecular Pain

Free access

Research article

First published 2009-03

Evaluating Cellular Impedance Assays for Detection of GPCR Pleiotropic Signaling and Functional Selectivity

Matthew F. Peters, Clay W. Scott

Journal of Biomolecular Screening

Free access

Research article

First published 2009-08

A Homogeneous Fluorescent Live-Cell Assay for Measuring 7-Transmembrane Receptor Activity and Agonist Functional Selectivity Through Beta-Arrestin Recruitment

Bonnie J. Hanson, Justin Wetter, Mark R. Bercher [...]

Journal of Biomolecular Screening

Free access

Research article

First published 2017-8

A Systematic Approach to Identify Biased Agonists of the Apelin Receptor through High-Throughput Screening

Danielle McAnally, Khandaker Siddiquee, Haleli Sharir [...]

Journal of Biomolecular Screening

Retricted access

Other

First published 2017-12

Homology Modeling of Ffa2 Identifies Novel Agonists that Potentiate Insulin Secretion

Stephanie R Villa, Rama K Mishra, Joseph L Zapater [...]

Journal of Investigative Medicine

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Research article

First published 2014-8

Integrating High-Content Analysis into a Multiplexed Screening Approach to Identify and Characterize GPCR Agonists

Yingjie Zhu, John Watson, Mengjie Chen [...]

Journal of Biomolecular Screening

Retricted access

Research article

First published 2021-5

Trends in application of advancing computational approaches in GPCR ligand discovery

Siyu Zhu, Meixian Wu, Ziwei Huang [...]

Experimental Biology and Medicine

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Research article

First published 2024-7

The 5-HT1A receptor biased agonists,NLX-204 and NLX-101,like ketamine,elicit rapid-acting antidepressant activity in the rat chronic mild stress model via cortical mechanisms

Mariusz Papp, Piotr Gruca, Ewa Litwa [...]

Journal of Psychopharmacology

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