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Open access

Research article

First published 2018-10

The synthetic glycolipid-based TLR4 antagonist FP7 negatively regulates in vitro and in vivo haematopoietic and non-haematopoietic vascular TLR4 signalling

Charys Palmer, Francesco Peri, Frank Neumann [...]

Innate Immunity

Open access

Research article

First published 2021-4

Synthetic glycolipid-based TLR4 antagonists negatively regulate TRIF-dependent TLR4 signalling in human macrophages

Charys Palmer, Fabio A Facchini, Richard PO Jones [...]

Innate Immunity

Open access

Research article

First published 2025

Preclinical development of the TLR4 antagonist FP12 as a drug lead targeting the HMGB1/MD-2/TLR4 axis in lethal influenza infection

Kari Ann Shirey, Alessio Romerio, Mohammed Monsoor Shaik [...]

Innate Immunity

Retricted access

Research article

First published 2018-12

HMGB1 Antagonist,Box A,Reduces TLR4,RAGE,and Inflammatory Cytokines in the Cornea of P. aeruginosa -Infected Mice

Sandamali A. Ekanayaka, Sharon A. McClellan, Xudong Peng [...]

Journal of Ocular Pharmacology and Therapeutics

Free access

Other

First published 2008-12

Continuous pharmacodynamic activity of eritoran tetrasodium,a TLR4 antagonist,during intermittent intravenous infusion into normal volunteers

Daniel P. Rossignol, Nancy Wong, Robert Noveck [...]

Innate Immunity

Open access

Research article

First published 2021

Isoimperatorin exerts anti-inflammatory activity by targeting the LPS-TLR4/MD-2-NF-κB pathway

Guirong Chen, Yunong Liu, Yubin Xu [...]

European Journal of Inflammation

Open access

Research article

First published 2023-02

Toll-like receptor 4 signaling pathway in sensory neurons mediates remifentanil-induced postoperative hyperalgesia via transient receptor potential ankyrin 1

Xiaowen Liu, Ruisong Gong, Liang Peng [...]

Molecular Pain

Free access

Other

First published 2004-08

Ligand-dependent Toll-like receptor 4 (TLR4)-oligomerization is directly linked with TLR4-signaling

Shin-ichiroh Saitoh, Sachiko Akashi, Takenao Yamada [...]

Innate Immunity

Free access

Other

First published 2007-08

The equine TLR4/MD-2 complex mediates recognition of lipopolysaccharide from Rhodobacter sphaeroides as an agonist

Katharina L. Lohmann, Michel L. Vandenplas, Michelle H. Barton [...]

Innate Immunity

Retricted access

Research article

First published 2020-12

Generation and Characterization of a Novel Anti-Rat TLR4/MD2 Antibody with Potent Neutralizing Activity In Vivo

Masahito Sato, Satoshi Takeuchi, Shinji Soga [...]

Monoclonal Antibodies in Immunodiagnosis & Immunotherapy

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