Sage Journals: Discover world-class research

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Research article

First published 2007-6

Chemopreventive and Bioenergetic Signaling Effects of PDK1/Akt Pathway Inhibition in a Transgenic Mouse Model of Prostate Cancer

Aaron M. Sargeant, Russell D. Klein, Robert C. Rengel [...]

Toxicologic Pathology

Free access

Research article

First published 2009-12

Development of High-Throughput TR-FRET and AlphaScreen ® Assays for Identification of Potent Inhibitors of PDK1

Zangwei Xu, Kumiko Nagashima, Dongyu Sun [...]

Journal of Biomolecular Screening

Free access

Research article

First published 2015-11

Tanshinone IIA Prevents Rat Basilar Artery Smooth Muscle Cells Proliferation by Inactivation of PDK1 During the Development of Hypertension

Zhi-Liang Yu, Jie-Ning Wang, Xiao-Hua Wu [...]

Journal of Cardiovascular Pharmacology and Therapeutics

Retricted access

Other

First published 2009-12

PDK1 Regulates Chemotaxis in Human Neutrophils

M. Yagi, A. Kantarci, T. Iwata [...]

Journal of Dental Research

Open access

Research article

First published 2017-2

Long non-coding RNA XIST promotes cell growth by regulating miR-139-5p/PDK1/AKT axis in hepatocellular carcinoma

Yichao Mo, Yaoyong Lu, Peng Wang [...]

Tumor Biology

Retricted access

Research article

First published 2019-6

Induction of Pyruvate Dehydrogenase Kinase 1 by Hypoxia Alters Cellular Metabolism and Inhibits Apoptosis in Endometriotic Stromal Cells

Hsiu-Chi Lee, Shih-Chieh Lin, Meng-Hsing Wu [...]

Reproductive Sciences

Open access

Research article

First published 2021

Computational Identification of Stearic Acid as a Potential PDK1 Inhibitor and In Vitro Validation of Stearic Acid as Colon Cancer Therapeutic in Combination with 5-Fluorouracil

Jonathan Mitchel, Pratima Bajaj, Ketki Patil [...]

Cancer Informatics

Open access

Research article

First published 2017-3

Staurosporine suppresses survival of HepG2 cancer cells through Omi/HtrA2-mediated inhibition of PI3K/Akt signaling pathway

Youming Ding, Bin Wang, Xiaoyan Chen [...]

Tumor Biology

Free access

Research article

First published 2004-06

Development of a Fluorescence Polarization Bead-Based Coupled Assay to Target Different Activity/Conformation States of a Protein Kinase

Zhuomei Lu, Zhizhang Yin, Linda James [...]

Journal of Biomolecular Screening

Open access

Research article

First published 2025

Molecular Docking Appraisal of Pleurotus ostreatus Phytochemicals as Potential Inhibitors of PI3K/Akt Pathway for Breast Cancer Treatment

Magdalene Eno Effiong, Mercy Bella-Omunagbe, Israel Sunmola Afolabi [...]

Bioinformatics and Biology Insights

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