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Open access

Review article

First published 2025-10

Predictive Modeling of Pharmacokinetic Drug–Drug and Herb–Drug Interactions in Oncology: Insights From PBPK Studies

Enes Emre Taş, Kutlu O. Ulgen

International Journal of Toxicology

Open access

Research article

First published 2025-3

Haloperidol dopamine receptor occupancy and antagonism correspond to delirium agitation scores and EPS risk: A PBPK-PD modeling analysis

Paul M Burkat

Journal of Psychopharmacology

Open access

Research article

First published 2022-3

Development of Physiologically Based Pharmacokinetic Model and Assessment of the Impact of Renal Underdevelopment in Preterm Infants on the Pharmacokinetics of Aminophylline

Hari Prabhath Tummala, Rachana Balusu, Sahithi Thotakura [...]

Journal of Pharmacology and Pharmacotherapeutics

Retricted access

Research article

First published 1996-3

In Vitro-based and In Vivo-hased Simulations of Benzene Uptake and Metabolism in Rats

Joost de Jongh, Bas J. Blaauboer

Alternatives to Laboratory Animals

Retricted access

Research article

First published 2001-6

The use of physiologically based models to integrate diverse data sets and reduce uncertainty in the prediction of perchlorate and iodide kinetics across life stages and species

Rebecca A Clewell, Elaine A Merrill, Peter J Robinson

Toxicology and Industrial Health

Free access

Research article

First published 2015-9

Toxicokinetic Model Development for the Insensitive Munitions Component 2,4-Dinitroanisole

Lisa M. Sweeney, Michelle R. Goodwin, Angela D. Hulgan [...]

International Journal of Toxicology

Retricted access

Research article

First published 2026

Precision dosing of clozapine: A physiologically based pharmacokinetic/pharmacodynamic model integrating genetic polymorphisms and clinical outcomes

Archana Mishra, Anand Srinivasan, Rituparna Maiti [...]

Journal of Psychopharmacology

Retricted access

Research article

First published 2014-9

Using physiologically-based pharmacokinetic-guided “body-on-a-chip” systems to predict mammalian response to drug and chemical exposure

Jong Hwan Sung, Balaji Srinivasan, Mandy Brigitte Esch [...]

Experimental Biology and Medicine

Free access

Research article

First published 1990-11

A Physiologically Based Pharmacokinetic Model of Parathion Based on Chemical-Specific Parameters Determined In Vitro

Lester G. Sultatos

International Journal of Toxicology

Retricted access

Research article

First published 2019-2

Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling Accurately Predicts the Better Bronchodilatory Effect of Inhaled Versus Oral Salbutamol Dosage Forms

Elin Boger, Markus Fridén

Journal of Aerosol Medicine and Pulmonary Drug Delivery

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