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Meeting report

First published 2025

Proceedings of the 2024 Classic Examples in Toxicologic Pathology XXXI

Charlotte Lempp, Emmanuelle Balme, Robert Lee Johnson [...]

Toxicologic Pathology

Retricted access

Research article

First published 2018-02

Cholesterol–GalNAc Dual Conjugation Strategy for Reducing Renal Distribution of Antisense Oligonucleotides

Fumito Wada, Tsuyoshi Yamamoto, Tetsuya Ueda [...]

Nucleic Acid Therapeutics

Open access

Brief report

First published 2021-08

Impact of Serum Proteins on the Uptake and RNAi Activity of GalNAc-Conjugated siRNAs

Saket Agarwal, Ruth Allard, Justin Darcy [...]

Nucleic Acid Therapeutics

Free access

Abstract

First published 1983-1

Light microscopic histochemical detection of terminal galactose and N-acetylgalactosamine residues in rodent complex carbohydrates using a galactose oxidase--Schiff sequence and peanut lectin--horseradish peroxidase conjugate.

B A Schulte, S S Spicer

Journal of Histochemistry & Cytochemistry

Open access

Research article

First published 2025-06

Mechanistic Insights into Hybridization-Based Off-Target Activity of GalNAc-siRNA Conjugates

Saket Agarwal, Elizabeth Taft, Micah Gauthier [...]

Nucleic Acid Therapeutics

Open access

Review article

First published 2018-10

The Nonclinical Safety Profile of GalNAc-conjugated RNAi Therapeutics in Subacute Studies

Maja M. Janas, Carole E. Harbison, Victoria K. Perry [...]

Toxicologic Pathology

Retricted access

Research article

First published 2021-12

Programmed Instability of Ligand Conjugation Manifold for Efficient Hepatocyte Delivery of Therapeutic Oligonucleotides

Chisato Terada, Fumito Wada, Mei Uchida [...]

Nucleic Acid Therapeutics

Retricted access

Review article

First published 2018-06

GalNAc-siRNA Conjugates: Leading the Way for Delivery of RNAi Therapeutics

Aaron D. Springer, Steven F. Dowdy

Nucleic Acid Therapeutics

Open access

Research article

First published 2024-02

Safety and Tolerability of GalNAc 3 -Conjugated Antisense Drugs Compared to the Same-Sequence 2′- O -Methoxyethyl-Modified Antisense Drugs: Results from an Integrated Assessment of Phase 1 Clinical Trial Data

Brenda F. Baker, Shuting Xia, Wesley Partridge [...]

Nucleic Acid Therapeutics

Open access

Research article

First published 2023-02

Integrated Assessment of Phase 2 Data on GalNAc 3 -Conjugated 2′- O -Methoxyethyl-Modified Antisense Oligonucleotides

Brenda F. Baker, Shuting Xia, Wesley Partridge [...]

Nucleic Acid Therapeutics

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