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Review article

First published 2019-9

CNS Safety Screening Under ICH S7A Guidelines Requires Observations of Multiple Behavioral Units to Assess Motor Function

David V. Gauvin, Zachary J. Zimmermann, Jill A. Dalton [...]

International Journal of Toxicology

Retricted access

Research article

First published 2026

5-Methoxy-N,N-Dimethyltryptamine: Functional Safety Pharmacology and Video-EEG Assessment of a Short-Acting Serotonergic Psychedelic in Beagle Canines

Amir Lotfi, Samantha Sparapani, Mylene Pouliot [...]

International Journal of Toxicology

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Research article

First published 2022-5

Investigational New Drug Enabling Nonclinical Safety Pharmacology Assessment of the Iminosugar UV-4,a Broad-Spectrum Host-Targeted Antiviral Agent

Jeffry Shearer, Gary Wolfe, Aruna Sampath [...]

International Journal of Toxicology

Open access

Review article

First published 2025-7

Discriminating evidence – use and misuse of the drug-discrimination test in abuse potential assessment of novel CNS drugs

David J Heal, Sharon Lesley Smith, Jane Gosden [...]

Journal of Psychopharmacology

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Research article

First published 2001-10

The Future of Imaging in Drug Discovery

Mark E. Schmidt

Journal of Pharmacy Practice

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Meeting report

First published 2025-6

Neurobiomarkers: Basic Aspects and Their Relevance in Nonclinical Studies

Andrea Greiter-Wilke, Nicolau Beckmann, Warren E. Glaab [...]

Toxicologic Pathology

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Research article

First published 2001-10

Pharmacokinetic and toxicology assessment of INTERCEPT (S-59 and UVA treated) platelets

V Ciaravino, T McCullough, A D Dayan

Human & Experimental Toxicology

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Research article

First published 2017-3

Development of a Functional Observational Battery in the Minipig for Regulatory Neurotoxicity Assessments

Miao Zhong, Catherine Shoemake, Amber Fuller [...]

International Journal of Toxicology

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Research article

First published 2013-7

A Nonclinical Safety Assessment of MnTE-2-PyP,a Manganese Porphyrin

Shayne C. Gad, Dexter W. Sullivan, James D. Crapo [...]

International Journal of Toxicology

Open access

Review article

First published 2011

Dalfampridine: Review of its Efficacy in Improving Gait in Patients with Multiple Sclerosis

M.A. Sahraian, A.H. Maghzi, M. Etemadifar [...]

Journal of Central Nervous System Disease

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