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Articles (19)

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1-10 of 19 results for Bayesian adaptive dose-finding design

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Select article: Using circulating tumor DNA as a novel biomarker of efficacy for dose-finding designs in oncology

Open access

Research article

First published 2025-8

Using circulating tumor DNA as a novel biomarker of efficacy for dose-finding designs in oncology

Xijin Chen, Pavel Mozgunov, Richard D Baird [...]

Statistical Methods in Medical Research

Select article: Combining Proof-of-Concept With Dose-Finding: Utilization of Adaptive Designs in Migraine Clinical Trials

Free access

Review article

First published 2008-8

Combining Proof-of-Concept With Dose-Finding: Utilization of Adaptive Designs in Migraine Clinical Trials

A Sagkriotis, J Scholpp

Cephalalgia

Select article: Modeling adverse event counts in phase I clinical trials of a cytotoxic agent

Retricted access

Research article

First published 2018-8

Modeling adverse event counts in phase I clinical trials of a cytotoxic agent

Daniel G Muenz, Thomas M Braun, Jeremy MG Taylor

Clinical Trials

Select article: Effective sample size for computing prior hyperparameters in Bayesian phase I–II dose-finding

Retricted access

Research article

First published 2014-12

Effective sample size for computing prior hyperparameters in Bayesian phase I–II dose-finding

Peter F Thall, Richard C Herrick, Hoang Q Nguyen [...]

Clinical Trials

Select article: A Bayesian quasi-likelihood design for identifying the minimum effective dose and maximum utility dose in dose-ranging studies

Open access

Research article

First published 2024-6

A Bayesian quasi-likelihood design for identifying the minimum effective dose and maximum utility dose in dose-ranging studies

Feng Tian, Ruitao Lin, Li Wang [...]

Statistical Methods in Medical Research

Select article: Novel Statistical Designs for Phase I/II and Phase II Clinical Trials With Dose-Finding Objectives

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Research article

First published 2014-9

Novel Statistical Designs for Phase I/II and Phase II Clinical Trials With Dose-Finding Objectives

Oleksandr Sverdlov, Weng Kee Wong

Therapeutic Innovation & Regulatory Science

Select article: Probability intervals of toxicity and efficacy design for dose-finding clinical trials in oncology

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Research article

First published 2021-3

Probability intervals of toxicity and efficacy design for dose-finding clinical trials in oncology

Xiaolei Lin, Yuan Ji

Statistical Methods in Medical Research

Select article: BOIN-ETC: A Bayesian optimal interval design considering efficacy and toxicity to identify the optimal dose combinations

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Research article

First published 2024-4

BOIN-ETC: A Bayesian optimal interval design considering efficacy and toxicity to identify the optimal dose combinations

Tomoyuki Kakizume, Kentaro Takeda, Masataka Taguri [...]

Statistical Methods in Medical Research

Select article: Development of a Bayesian response-adaptive trial design for the Dexamethasone for Excessive Menstruation study

Open access

Research article

First published 2017-12

Development of a Bayesian response-adaptive trial design for the Dexamethasone for Excessive Menstruation study

Christian Holm Hansen, Pamela Warner, Richard A Parker [...]

Statistical Methods in Medical Research

Select article: A Bayesian phase I/II biomarker-based design for identifying subgroup-specific optimal dose for immunotherapy

Retricted access

Research article

First published 2022-6

A Bayesian phase I/II biomarker-based design for identifying subgroup-specific optimal dose for immunotherapy

Beibei Guo, Yong Zang

Statistical Methods in Medical Research

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