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Retricted access

Research article

First published 2017-03

Nonclinical Pharmacology/Toxicology Study of AAV8.TBG.mLDLR and AAV8.TBG.hLDLR in a Mouse Model of Homozygous Familial Hypercholesterolemia

Jenny A. Greig, Maria P. Limberis, Peter Bell [...]

Human Gene Therapy Clinical Development

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Research article

First published 2017-02

Efficient Gene Delivery and Expression in Pancreas and Pancreatic Tumors by Capsid-Optimized AAV8 Vectors

Min Chen, Kyungah Maeng, Akbar Nawab [...]

Human Gene Therapy Methods (Part B)

Open access

Research article

First published 2013-02

Gene Therapy for Mucopolysaccharidosis Type VI Is Effective in Cats Without Pre-Existing Immunity to AAV8

Rita Ferla, Thomas O'Malley, Roberto Calcedo [...]

Human Gene Therapy

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Research article

First published 2013-05

Kinetics of Adeno-Associated Virus Serotype 2 (AAV2) and AAV8 Capsid Antigen Presentation In Vivo Are Identical

Yi He, Marc S. Weinberg, Matt Hirsch [...]

Human Gene Therapy

Open access

Research article

First published 2021-07

Host Immune Responses after Suprachoroidal Delivery of AAV8 in Nonhuman Primate Eyes

Sook Hyun Chung, Iris Natalie Mollhoff, Alaknanda Mishra [...]

Human Gene Therapy

Free access

Research article

First published 2015-1

Comparative Antiatherogenic Effects of Intravenous AAV8- and AAV2-Mediated ApoA-IMilano Gene Transfer in Hypercholesterolemic Mice

Fang Tian, Lai Wang, Ana Arias [...]

Journal of Cardiovascular Pharmacology and Therapeutics

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Research article

First published 2018-07

AAV8 Gene Therapy Rescues the Newborn Phenotype of a Mouse Model of Crigler–Najjar

Jenny A. Greig, Jayme M.L. Nordin, Christine Draper [...]

Human Gene Therapy

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Research article

First published 2026-4

Exploring Development Options of a Polishing Chromatography Step for AAV7 and AAV8

Xiaotong Fu, Colin Haws, Darren Begley [...]

Human Gene Therapy

Open access

Research article

First published 2015-06

Intravenous AAV8 Encoding Urocortin-2 Increases Function of the Failing Heart in Mice

N. Chin Lai, Mei Hua Gao, Dimosthenis Giamouridis [...]

Human Gene Therapy

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Research article

First published 2017-03

Non-Clinical Study Examining AAV8.TBG.hLDLR Vector-Associated Toxicity in Chow-Fed Wild-Type and LDLR +/− Rhesus Macaques

Jenny A. Greig, Maria P. Limberis, Peter Bell [...]

Human Gene Therapy Clinical Development

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