Mechanism of muscle contraction

Abstract

This work is the first attempt to propose a complex model of muscle contraction in which different aspects of the sarcomere shortening are collected into a logical entity. Proposed are some suggestions to answer some fundamental questions concerning the molecular mechanism of muscle contraction, such as the following: “of which part of the myosin molecule does the crossbridge consist?”, “how does the crossbridge act?”, “what are two heads of the myosin molecule needed for?”, “in what way is the metabolic energy of ATP converted into the mechanical work of muscle contraction?”, “does the actin filament influence have a passive or active role in the process of muscle contraction?”, “what is the role of the third filament – a connecting one?”, “in what way is muscle relaxation generated?”.