Abstract
In this paper, norathyriol has been synthesised from 2-bromo-4,5-dimethoxybenzoic acid and 1,3,5-trimethoxybenzene by a three-step sequence of transformations involving a Friedel–Crafts acylation with cyclisation and demethylation. The procedure was facile and should be easily scaled-up. The overall yields reached approximately 70%.
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