Abstract
Knoevenagel reaction of 2-cyanoacetylpyrrole with aromatic aldehydes afforded 2-(3-aryl-2-cyanopropenoyl)-1-methylpyrrole in 81–94% yields in ethanol catalysed by KF/Al2O3 under microwave irradiation. This method has the advantages of simplicity, good yields and low costs.
Keywords
References
1.
Song A.
,
Wanga X.
, and
Lam K.S.
, Tetrahedron Lett. , 2003 , 44 , 1755 .
2.
Balalaie S.
,
Sheikh A.M.
, and
Bararjanian M.
, Catal. Commun. , 2007 , 8 , 1724 .
3.
Bigi F.
,
Chesini L.
,
Maggi R.
, and
Sartori G.
, J. Org. Chem. , 1999 , 64 , 1033 .
4.
Zahouily M.
,
Salah M.
,
Bahlaouane B.
,
Rayadh A.
,
Houmam A.
,
Hamed E.A.
, and
Sebti S.
, Tetrahedron , 2004 , 60 , 1631 .
5.
Liang F.
,
Pu Y.
,
Kurata T.
,
Kido J.
, and
Nishide H.
, Polymer , 2005 , 46 , 3767 .
6.
Narsaiah A.V.
,
Basak A.K.
,
Visali B.
, and
Nagaiah K.
, Synth. Commun. , 2004 , 34 , 2893 .
7.
Wada S.
, and
Suzuki H.
, Tetrahedron Lett. , 2003 , 44 , 399 .
8.
Seki T.
, and
Onaka M.
, Journal of Molecular Catalysis A: Chem. , 2007 , 263 , 115 –120 .
9.
Zhang M.
,
Zhang A.Q.
, and
Deng Z.H.
, J. Chem. Res. , 2005 , 69 .
10.
Narasaiha A.V.
, and
Nagaiah K.
, Synth. Commun. , 2003 , 33 , 3825 .
11.
Reddy T.I.
, and
Varma R.S.
, Tetrahedron Lett. , 1997 , 38 , 1721 .
12.
Lu Y.
,
Ren Z.
,
Cao W.
, and
Gao M.
, Synth. Commun. , 2004 , 34 , 2047 .
13.
Boruah M.
,
Konwar D.
, and
Sharma S.D.
, Tetrahedron Lett. , 2007 , 48 , 4535 .
14.
Movassagh B.
, and
Shokri S.
, Tetrahedron Lett. , 2005 , 46 , 6923 .
15.
Murugan C.
, and
Bajaj H.C.
, Fuel Process. Technol. , 2011 , 92 , 77 .
16.
Li J.T.
,
Xu W.Z.
,
Chen G.F.
, and
Li T.S.
, Ultrason. Sonochem. , 2005 , 12 , 473 .
17.
Slatt J.
,
Romero I.
, and
Bergman J.
, Synthesis , 2004 , 2760 .