Free accessResearch articleFirst published online 2010-4
L-Proline Triflate as an Efficient and Reusable Catalyst for the One-Pot Synthesis of 2,4,5-Trisubstituted Imidazoles and 1,2,4,5-Tetrasubstituted Imidazoles
L-Proline triflate has been used as an efficient catalyst for an improved and rapid one-pot synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles in good yields. The benefit of this approach is its operational simplicity and the catalyst can be easily recovered and reused without any loss of activity.
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