Abstract
The title compound was synthesised by the reaction of N-ethoxycarbonyl-N'-(2,4,6–tribromo-phenyl)thiourea with copper chloride in ethanol solution. Cyclisation of the ethoxycarbonylthiourea formed the ethyl 4,6-dibromo benzothiazol-2-ylcarbamate.
References
1.
Bradshaw T.D.
,
Wrigley S.
,
Shi D.-F.
,
Schultz R. J.
,
Paull K. D.
, and
Stevens M. F. G.
, Br. J. Cancer. , 1998 , 77 , 745 .
2.
O'Brien S.E.
,
Browne H. L.
,
Bradshaw T. D.
,
Westwell A. D.
,
Stevens M. F. G.
, and
Laughton C. A.
, Org. Biomolec. Chem. , 2003 , 1 , 493 .
3.
Bradshaw T.D.
,
Bibby M. C.
,
Double J. A.
,
Fichtne I.
,
Copper P. A.
,
Alley M. C.
, and
Donohue S.
, Mol. Cancer Therapeutics. , 2002 , 1 , 239 .
4.
Ben-Alloum A.
,
Bakkas S.
, and
Soufiaoui M.
, Tetrahedron Lett. , 1997 , 38 , 6395 .
5.
Hutchinson I.
,
Stevens M. F. G.
, and
Westwell A. D.
, Tetrahedron Lett. , 2000 , 41 , 425 .
6.
Spitulnik M.J.
, Synthesis. , 1976 , 730 .
7.
Roe A.
, and
Tucker W. P. J.
, J. Heterocycl. Chem. , 1965 , 2 , 148 .
8.
Mourtas S.
,
Gatos D.
, and
Barlos K.
, Tetrahedron Lett. , 2001 , 42 , 2201 .
9.
Zhang Y.M.
,
Wei T. B.
, and
Gao L. M.
, Synth. Commun. , 2001 , 31 , 3099 .
10.
Zhang Y.M.
,
Xian L
,
Wei T. B.
, and
Cai L. X.
, Acta. Cryst. , 2003 , E59 , 817 .
11.
Zhang Y.M.
,
Wei T. B.
,
Xian L.
,
Lin Q.
, and
Yu K. B.
, Acta. Cryst. , 2003 , E59 , 905 .
12.
Zhang Y.M.
,
Xian L.
, and
Wei T. B.
, Acta Cryst. , 2003 , C59 , 473 .
13.
Xian L.
,
Wei T. B.
, and
Zhang Y. M.
, J. Coord. Chem. , 2004 , 57 , 453 .
14.
Zhang Y.M.
,
Xian L.
,
Wei T. B.
, and
Yu K. B.
, J. Chem. Res (S) , 2003 , 798 .
15.
Lin Q.
,
Zhang Y. M.
,
Wei T. B.
, and
Wang H.
, J. Chem. Res. , 2004 , 298 .
16.
All the X-ray crystal structural data are available in CCDC (CCDC No. 259198)
17.
Sheldrick G.M.
, Acta Cryst. A46 , 1990 , 467
18.
Sheldrick G.M.
, SHELXL97. University of Göttingen , Germany , 1997 .