Sage Journals: Discover world-class research

Abstract

(E)-Cinnamonitriles have been synthesised stereoselectively in high yields via Heck arylation of acrylonitrile with aryl iodides catalysed by a silica-supported bidentate arsine palladium(0) complex. This polymeric palladium(0) complex can be recovered and reused without noticeable loss of activity.

Keywords

Heck arylation supported palladium catalyst bidentate palladium(0) complex stereoselective synthesis

References

Georg

G.I.

, and Pfeifer

S. A.

, Tetrahedron Lett., 1985, 26, 2739.

Francoise

T.B.

, and Andre

, Synthesis, 1979, 884.

Hulkenberg

, and Troost

J. J.

, Tetrahedron Lett., 1982, 23, 1505.

Huang

, Pi

J. H.

, and Huang

Z. Z.

, Phosphorus Sulfur Silicon Relat. Elem., 1992, 67, 177.

Guo

, and Zhang

, J. Chem. Res., 1999, 342.

Ziegler

C.B.

, and Heck

R. F.

, J. Org. Chem., 1978, 43, 2941.

Heck

R.F.

, Acc. Chem. Res., 1979, 12, 146.

Heck

R.F.

, Pure Appl. Chem., 1978, 50, 691.

Cai

, Huang

, Zhao

, and Song

, J. Organomet. Chem., 2003, 682, 20.

10.

Pastushak

N.O.

, Stadniichuk

N. F.

, and Dombrovskii

A. V.

, Zh. Ohshch. Khim., 1963, 33, 2950.

11.

Zhao

, Cai

M. Z.

, and Peng

C. Y.

, Synth. Commun., 2002, 32, 3419.

Novel stereoselective synthesis of ( E )-cinnamonitriles via Heck arylation of acrylonitrile catalysed by a silica-supported bidentate arsine palladium(0) complex

Abstract

Keywords

References