(22R) and (22S) 3-Oxo-23,24-dinorchol-4-ene-22-cyanohydrin have been synthesised from 3-oxo-23,24-dinorchol-4-ene-22-al and the crystal structure of the (22R) epimer has been determined by X-ray crystallography.
DuaxW.L., WeeksC. M., and RohrerD. C., Topics in Stereochemistry, ElielE.L., and AllingerN. (eds), Vol. 9, 1976, p. 271.
3.
HeylF.W., and HerrM. E., J. Am. Chem. Soc., 1950, 72, 2617.
4.
OtwinowskiZ., and MinorW., Processing of X-ray Diffraction Data Collected in Oscillation Mode, Methods in Enzymology, Vol. 276: Macromolecular Crystallography, part A, pp. 307–326. CarterC. W.Jr., and SweetR. M., (eds), Academic Press, 1997.
5.
HooftR.COLLECT Data collection software.Nonius B.V., Delft, The Netherlands, 1998.
6.
AltomareA., BurlaM. C., CamalliM., CascaranoG. L., GiacovazzoC., GuagliardiA., MoliterniA. G. G., PolidoriG., and SpagnaR., J. Appl. Cryst., 1999, 32, 115.
7.
SheldrickG.M.SHELX97-2. Program for the Refinement of Crystal Structures.Univ. of Göttingen, Germany, 1998.
8.
SpekA.L.PLATON. Program for geometrical analysis of X-ray molecular structure.Univ. of Utrecht, The Netherlands, 2001. Version 101201.
