A Practical Palladium-Catalysed Heteroannulation of 2-bromobenzaldehyde with Alcohols and Carbon Monoxide Leading to 3-alkoxy-3 H -isobenzofuran-1-ones
Free accessResearch articleFirst published online November, 2002
A Practical Palladium-Catalysed Heteroannulation of 2-bromobenzaldehyde with Alcohols and Carbon Monoxide Leading to 3-alkoxy-3 H -isobenzofuran-1-ones
2-Bromobenzaldehyde is carbonylatively cyclised with alcohols in the presence of a catalytic amount of PdCl2(PPh3)2/PPh3 together with a base to afford the corresponding 3-alkoxy-3H-isobenzofuran-1-ones in good yields.
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