SunT, JacksonS, HaycockJW, MacNeilS. Culture of skin cells in 3D rather than 2D improves their ability to survive exposure to cytotoxic agents. J Biotechnol, 2006; 122:372-, doi:10.1016/j.jbiotec.2005.12.021.
2.
VocansonM, HenninoA, RozièresA, et al.Effector and regulatory mechanisms in allergic contact dermatitis. Allergy, 2009; 64:1699-714, doi: 10.1111/j.1398-9995.2009.02082.x.
3.
VocansonM, Cluzel-TailhardatM, PoyetG, et al.Depletion of human peripheral blood lymphocytes in CD25+ cells allows for the sensitive in vitro screening of contact allergens. J Invest Dermatol, 2008; 128:2119-22, doi:10.1038/jid.2008.15.
4.
VocansonM, HenninoA, RozieresA, et al.Inducible costimulator (ICOS) is a marker for highly suppressive antigen-specific T cells sharing features of TH17/TH1 and regulatory T cells. J Allergy Clin Immunol, 2010; 126:280-9, 289e1-7, doi:10.1016/j.jaci.2010.05.022.
5.
ToebakMJ, GibbsS, BruynzeelDP, et al.Dendritic cells: biology of the skin. Contact Dermatitis, 2009; 60:2-20, doi:10.1111/j.1600-0536. 2008.01443.x.
6.
CorsiniE, MitjansM, GalbiatiV, et al.Use of IL-18 production in a human keratinocyte cell line to discriminate contact sensitizers from irritants and low molecular weight respiratory allergens. Toxicol In Vitro, 2009; 23:789-96, doi:10.1016/j.tiv.2009.04.005.
7.
SpiekstraSW, Dos SantosGG, ScheperRJ, GibbsS. Potential method to determine irritant potency in vitro—comparison of two recon-structed epidermal culture models with different barrier competency. Toxicol In Vitro, 2009; 23:349-55, doi:10.1016/j.tiv.2008.12.010.
8.
OuwehandK, SpiekstraSW, ReindersJ, et al.Comparison of a novel CXCL12/CCL5 dependent migration assay with CXCL8 secretion and CD86 expression for distinguishing sensitizers from non-sensitizers using MUTZ-3 Langerhans cells. Toxicol In Vitro, 2010; 24:578-85, doi:10.1016/j.tiv.2009.10.014.
9.
MartinSF, EsserPR, SchmuckerS, et al.T-cell recognition of chemicals, protein allergens and drugs: towards the development of in vitro assays Cell Mol Life Sci. 2010; 67:4171-84, doi:10.1007/s00018-010-0495-3.
10.
NatschA, EmterR. Skin sensitizers induce antioxidant response element dependent genes: application to the in vitro testing of the sensitization potential of chemicals. Toxicol Sci, 2008; 102:110-9, doi: 10.1093/toxsci/kfm259.
11.
NatschA. The Nrf2-Keap1-ARE toxicity pathway as a cellular sensor for skin sensitizers—functional relevance and a hypothesis on innate reactions to skin sensitizers. Toxicol Sci, 2010; 113:284-92, doi: 10.1093/toxsci/kfp228.
12.
ReuterH, SpiekerJ, GerlachS, et al.In vitro detection of contact allergens: development of an optimized protocol using human peripheral blood monocyte-derived dendritic cells. Toxicol In Vitro, 2011; 25:315-23, doi:10.1016/j.tiv.2010.09.016.
13.
SaffordRJ. The Dermal Sensitisation Threshold—a TTC approach for allergic contact dermatitis. Regul Toxicol Pharmacol, 2008; 51: 195-200, doi:10.1016/j.yrtph.2008.02.010.
14.
SaffordBJ, AptulaAO, GilmourN. Refining the Dermal Sensitisation Threshold: a TTC approach for allergic contact dermatitis. Contact Dermatitis, 2010; 63:36-7.
15.
AleksicM, ThainE, RogerD, et al.Reactivity profiling: covalent modification of single nucleophile peptides for skin sensitization risk assessment. Toxicol Sci, 2009; 108:401-11, doi:10.1093/toxsci/kfp030.
16.
McKimJM Jr, KellerDJ 3rd, GorskiJR. A new in vitro method for identifying chemical sensitizers combining peptide binding with ARE/EpRE-mediated gene expression in human skin cells. Cutan Ocul Toxicol, 2010; 29:171-92, doi:10.3109/15569527.2010.483869.
17.
RosenkrantzHS, KlopmanG, ChankongV, et al.Prediction of environmental carcinogens: a strategy for the mid-1980s. Environ Mutagen, 1984; 6:231-58, doi: 10.1002/em.2860060212.
