Comment: Drug-Drug Interaction Between Clopidogrel and the Proton Pump Inhibitors

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References

1. Norgard

Mathews

Wall

GC.

Drug-drug interaction between clopidogrel and the proton pump inhibitors. Ann Pharmacother 2009;43:1266–74. Epub 26 May 2009. DOI 10.1345/aph.1M051.

2. Juurlink

Gomes

A population-based study of the drug interaction between proton pump inhibitors and clopidogrel. CMAJ 2009;180:713–8. DOI 10.1503/cmaj.082001.

3. Ho

Maddox

Wang

Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndromes. JAMA 2009;301:937–44.

4. Medco MediaRoom. New study: a common class of GI medications reduces protection against heart attack in patients taking widely prescribed cardiovascular drug. http://medco.mediaroom.com/index.php?s=43&item=352 (accessed 2009 May 25).

5. O'Donoghue

Braunwald

Antman

Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials. Lancet 2009;374:989–97. DOI 10.1016/S0140-6736(09)61525-7.