Comment: Neurologic,Psychological,and Aggressive Disturbances with Sildenafil

Lue TF . Erectile dysfunction. N Engl J Med 2000;342: 1802–13.

Milman HA Arnold SB . Neurologic, psychological, and aggressive disturbances with sildenafil. Ann Pharmacother 2002;36: 1129–34.

Rosen RC Beck JG . Patterns of sexual arousal: psychophysiological processes and clinical applications. New York: Guilford Press, 1988.

Nelson RJ Demas GE Huang PL Fishman MC Dawson VL Dawson TM Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase. Nature 1995;378: 383–6.

Giordano D De Stefano ME Citro G Modica A Giorgi M . Expression of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in mouse tissues and cell lines using an antibody against the enzyme amino-terminal domain. Biochim Biophys Acta 2001;1539: 16–27.

Kotera J Fujishige K Omori K . Immunohistochemical localization of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in rat tissues. J Histochem Cytochem 2000;48: 685–93.