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Abstract

The amino acid sequence of mouse p53 was measured according to two-and three-amino-acid sequences. The measured frequency and probability were compared with predicted frequency and probability. Of 389 two-amino-acidsequencesinmousep53,85 (21.851%) and27 (6.941%) sequences can be explained by the predicted frequency and probability accordingto a purely random mechanism. Of 188 non-appearing two-amino-acid sequences in mouse p53, 86 (45.745%) and 32 (17.021%) can be explained by the predicted frequency and probability according to a purely random mechanism; no more than two-amino-acid sequences inmousep53 canbe explained by a purelyrandom mechanism.

Keywords

amino acid sequence mouse p53 Markov chain probability

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Frequency and Markov chain analysis of amino acid sequences of mouse p53

Abstract

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References