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Abstract

There is a high prevalence of congenital heart disease in patients with Down syndrome. Atrioventricular (AV) canal defects, ventricular septal defects, and a patent ductus arteriosus are most commonly seen. The authors present a patient with a unique constellation of findings, including an AV canal defect, pulmonary artery sling, and an aberrant right subclavian artery diagnosed on a screening echocardiogram. Additional imaging modalities confirmed this atypical concurrence of congenital heart defects and also proved the accuracy of echocardiography in diagnosing rare combinations of congenital heart disease.

Keywords

left pulmonary artery sling endocardial cushion defect Down syndrome aberrant right subclavian artery ventricular septal defect

References

Malini S. , Ramachandra N. : Possible risk factors for Down syndrome and sex chromosomal aneuploidy in Mysore, South India. Indian J Hum Genet 2007 ;13:102-108.

Eidem BW , Jones C. , Cetta F. : Unusual association of hypertrophic cardiomyopathy with complete atrioventricular canal defect and Down syndrome. Tex Heart Inst J 2000;27:289-291.

Goldstein WB : Aberrant right subclavian artery in Mongolism . Am J Roentgenol 1965;95:131-134.

Yeager SB , Chin AJ , Sanders SP : Two-dimensional echocardiographic diagnosis of pulmonary artery sling in infancy . J Am Coll Cardiol 1986;7:625-629.

KirkHammer AC Esophagography in Anomalies of the Aortic Arch System. Baltimore, Williams & Wilkins, 1969.

Freeman SB , Taft LF , Dooley KJ , et al: Population-based study of congenital heart defects in Down syndrome . Am J Med Genet 1998;80:213-217.

Cooper RS : Endocardial cushion defects: embryology, anatomy and pathophysiology. Adv Cardiol 2004;41:118-126.

Wahl A. , Meier B. : Patent foramen ovale and ventricular septal defect closure. Heart 2009;95:70-82.

Zapata H. , Edwards JE , Titus JL : Aberrant right subclavian artery with left aortic arch: associated cardiac anomalies. Pediatr Cardiol 1993;14:159-161.

10.

Goldman L. : Cecil Textbook of Medicine. 21st ed. Philadelphia, W. B. Saunders, 2000 .

11.

Davies M. , Guest PJ : Developmental abnormalities of the great vessels of the thorax and their embryological basis. Br J Radiol 2003;76:491-502.

12.

King HA , Walker D. : Pulmonary artery sling. Thorax 1984; 39:462-465.

13.

Loureiro M. , Moreira J. , Vaz T. , Ribeiro A. , Monterroso J. , Areias JC : Anomalous origin of the left pulmonary artery (sling): a case report and review of the literature [in Portuguese]. Rev Port Cardiol 1998;17:811-815.

14.

Brenner D. , Hall E. : Computed tomography: an increasing source of radiation exposure. N Engl J Med 2007;357: 2277-2284.

15.

Witt SA : Pediatric echocardiography. J Diagn Med Sonography 2005;21:216-231.

16.

Tsai-Goodman B. , Geva T. , Odegard KC , et al: Clinical role, accuracy, and technical aspects of cardiovascular magnetic resonance imaging in infants. Am J Cardiol 2004;94:69-74.

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Atrioventricular Canal Defect,Pulmonary Artery Sling,and Aortic Arch Anomaly in a Patient With Down Syndrome

Abstract

Keywords

References

Supplementary Material