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Abstract

Cervical carcinoma or cancer of the cervix (a canal connecting the uterus to the vagina) is the second most common cancer in women ages 35 to 55. Gestational trophoblastic disease (GTD), also known as gestational trophoblastic neoplasia (GTN), does not develop from the uterine cells like cervical carcinoma; it is an abnormal trophoblastic proliferation inside the uterus. Cervical cancer can be a very serious disease, yet if it is detected early, it can be treated. Through the use of a Papanicolaou (Pap) smear test, abnormal cells of the cervix can be detected. Over the years, normal cervical cells can turn into precancerous cells and later change into cancer cells. If the cells are invasive, they can become cancerous in less than a year. In some cases, sonography can be used to better delineate the extent of the disease . Cervical cancer can be caused by a human papillomavirus through sexual intercourse. As the woman's age of her first intercourse decreases, the chance of cervical cancer increases, especially with multiple partners and no regular Pap smears.

Keywords

carcinoma cervix human papillomavirus Papanicolaou smear gestational trophoblastic neoplasia

References

Normal lab values. January 21, 2008. Available at: http://www.mtworld.com/tools_resources/lab_values.html .

National Cancer Institute: Cervical cancer (PDQ®): treatment . Available at: http://www.cancer.gov/cancertopics/pdq/treatment/cervical/Patient . Accessed January 2, 2007.

American Cancer Society : What is gestational trophoblastic disease? Available at: http://www.cancer.org/docroot/cri/content/cri_2_4_1x_what_are_gestational_trophoblastic_disease_49.asp?sitearea . Accessed July 15, 2007.

American Cancer Society : How is gestational trophoblastic disease diagnosed? Available at: http://www.cancer.org/docroot/CRI/content/CRI_2_4_3X_How_is_gestational_trophoblastic_disease_diagnosed_49.asp . Accessed July 15, 2007.

Zelko G. : Cancer of the cervix. In Merck Manual of Medical Information . Home ed. New York : Pocket; 1997.

Preidt R. : Girls should receive cervical cancer vaccine: experts. Available at: http://www.nlm.nih.gov/medlineplus/news/fullstory_44118.html. Accessed January 24, 2007.

US Food and Drug Administration : HPV (human papillomavirus). Available at: http://www.fda.gov/womens/getthefacts/hpv.html. Accessed January 7, 2007.

American Cancer Society : Can cervical cancer be prevented?" Available at: http://www.cancer.org/docroot/CRI/content/CRI_2_4_2X_Can_cervical_cancer_be_prevented_8.asp. Accessed October 30, 2006.

Widdice LE , Kahn JA : Using the new HPV vaccines in clinical practice. Cleve Clin J Med 2006;73:929-935.

10.

Zimet GD : Improving adolescent health: focus on HPV vaccine acceptance. J Adolesc Health 2005;37(suppl): S17-S23.

Cervical Carcinoma

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