Abstract
Objective:
To examine the relationship of the frequency of daily doses and medication compliance for hypertensive patients.
Design:
Retrospective study, nonrandomized control trial.
Setting:
Rural, general community.
Participants:
Convenience sample of 55 outpatients who were prescribed antihypertensive therapy exclusively and whose therapy had been consistent for at least 14 months.
Data Extraction:
Pharmacy records were accessed to determine the medication compliance of these participants.
Main Outcome Measure:
Medication compliance differences between participants who were on a once-a-day antihypertensive regimen versus a two-or-more × a day regimen.
Results:
Patients in the once-a-day regimen group were significantly more compliant than those in the two-or-more × a day group.
Conclusions:
Consideration must be given to simplification of medication regimens to improve compliance. J Pharm Technol 1994;10:115–7.
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