The diagnosis of esophagogastric outlet obstruction (EGJOO) includes a heterogenous group of disorders with a wide variation in clinical course ranging from spontaneous resolution to achalasia. EGJOO can be subdivided into primary EGJOO or secondary EGJOO in which structural, infiltrative, or medication-related causes can be implicated. Recently, research studies have focused on further phenotyping of patients with EGJOO using provocative testing during high resolution esophageal manometry (HRM) as well as non-manometric adjuvant testing. We will review the various modalities used for diagnosis and assessment of EGJOO as well as the available treatments.
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