Plasma medicine offers an innovative and advanced physical approach to wound care that uniquely combines wound antimicrobial effects (primary goal) and accelerated regeneration of injured tissue (secondary goal). This review explores its transformative potential in modern medicine, demonstrating how this technology can enhance wound healing, reduce microbial load, and improve clinical outcomes. A certified plasma device provides an add-on technology that has the potential to improve current wound care medical procedures by integrating findings from basic research, preclinical models, and clinical applications. This review underscores the significant role of plasma medicine in transforming wound care practices by bridging fundamental research, preclinical validation, regulatory compliance, and clinical application, paving the way for safer, more effective, and minimally invasive treatment strategies.
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