A Children’s Oncology Group Survey Exploring Practices and Barriers to Sperm Banking for Post-Pubertal Males with Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia

Abstract

This study examined sperm banking (SB) practices and barriers for post-pubertal males with high-risk acute lymphoblastic leukemia (ALL) prior to chemotherapy. A cross-sectional survey of 2345 Children’s Oncology Group oncologists across the U.S., Canada, Australia, and New Zealand yielded 572 responses. While 78% offer SB, common barriers include timing (70%) and patient health (44%). Most institutions offering SB have a dedicated oncofertility team (57%), and 86% are medium- or large-sized, suggesting greater resource availability. These results extend prior research by identifying actionable barriers and informing targeted interventions to improve access to FP for post-pubertal males with ALL.