Cognitive impairment is a common complaint in an aging society, should be differentiated clinically into chronic and rapidly progressive categories. This case of Creutzfeldt-Jakob disease (CJD) illustrates the typical clinical features, imaging and EEG changes of an important cause of rapidly progressive dementia.
World Health Organization. Global surveillance, diagnosis and therapy of human transmissible spongiform encephalopathies: Report of a WHO consultation [Internet]. Geneva: World Health Organization. 1998 Feb 9–11 [cited 2010 Jan 12]. Available from: http://www.who.int/csrl/resources/publications/bse/WHO_EMC_ZDI_98_9/en/.
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YoungGSGeschwindMDFischbeinNJMartindaleJLHenryRGLiuS. Diffusion-weighted and fluid-attenuated inversion recovery imaging in Creutsfelt-Jakob disease: High sensitivity and specificity for diagnosis. AJNR Am J Neuroradiol. 2005;26(6): 1551–62.
