Advances in Neuroimaging in Alzheimer's Disease and other Dementias

Berr C Wancata J Ritchie K : Prevalence of dementia in the elderly in Europe. Eur Neuropsychopharmacol 2005.

Jönsson L Berr C : Cost of dementia in Europe. European Journal of Neurology 12: 50–53, 2005.

Boada M Peña-Casanova J Bermejo F : Costs of health care resources of ambulatory-care patients diagnosed with Alzheimer's disease in Spain. Med Clinica 113: 690–5, 1999.

Petersen RC Doody R Kurz A : Current concepts in mild cognitive impairment. Arch Neurol 58: 1985–1992, 2001.

Markesbery WR : Alzheimer's disease. In: Asbury AK McKhann GM McDonald WI , eds. Diseases of the Nervous System: Clinical Neurobiology, 2nd ed. Philadelphia: Saunders 1992: 795–803.

Atiya M Hyman BT Albert MS : Structural magnetic resonance imaging in established and prodromal Alzheimer Disease: A Review. Alz Dis Assoc Disord 17: 177–195, 2003.

Gomez-Isla T Price J McKeel D : Profound loss of layer II enthorrinal cortex neurons occurs in very mild Alzheimer's disease. J Neurosci 16: 4491–4500, 1996.

West MJ Coleman PD Flood DG : Differences in the pattern of hippocampus neuronal loss in normal ageing and Alzheimer's disease. Neurology 49: 786–794, 1997.

Scheltens Ph Leys D Barkhof F : Atrophy of medial temporal lobes on MRI in “probable” Alzheimer's disease and normal ageing: diagnostic value and neuropsychological correlates. J Neurol Neurosurg Psychiatry 55: 967–972, 1992.

Jack CR Petersen RC Xu Y : Rates of hippocampal atrophy correlate with change in clinical status in ageing and AD. Neurology 55: 484–489, 2000.

Smith SM De Stefano N Jenkinson M : Normalized accurate measurement of longitudinal brain change. J Comput Assist Tomogr 23: 466–475, 2001.

Gomez-Anson B Alayrach E Caprile C : Quantitation of global and segmented brain volumes on MRI in patients with Mild Cognitive Impairment, Alzheimer's Disease and ageing controls using automated software (FSL, Oxford): cross-sectional and longitudinal studies. To be presented at the XXX ESNR Congress, Barcelona 2005.

Karas GB Scheltens P Rombouts SA : Global and local grey matter loss in mild cognitive impairment and Alzheimer's disease. Neuroimaging 23: 708–16, 2004.

Good CD Johnsrude IS Ashburner J : A Voxel-Based Morphometry study of ageing in 465 normal adult human brains. Neuroimage 14: 21–36, 2001.

Pennanen C Testa C Laakson MP : A voxel based morphometry study on mild cognitive impairment. J Neurol Neurosurg Psychiatry 76: 11–4, 2005.

Baron JC Chetelat G Desgranges B : In vivo mapping of grey matter loss with voxel-based morphometry in mild Alzheimer's disease. Neuroimage 14: 298–309, 2001.

Fox NC Freeborough PA Rossor MN : Visualisation and quantification of rates of atrophy in Alzheimer's disease. Lancet 348: 94–97, 1996.

Fox NC Warrington EK Seiffer AL : Presymptomatic cognitive deficits in individuals at risk of familial Alzheimer's disease. A longitudinal prospective study. Brain 121: 1631–1639, 1998.

Urenjak J Willians SR Gadian DG : proton nuclear magnetic resonance spectroscopy unambiguously identifies different neural cell types. J Neurosci 13: 981–9, 1993.

Valenzuela MJ Sachdev P : Magnetic resonance spectroscopy in AD. Neurology 56: 592–598, 2001.

Minoshima S Giordani B Berent S : Metabolic reduction in the posterior cingulated cortex in very early Alzheimer's disease. Ann Neurol 42: 85–94, 1997.

Catani M Cherubini A Howard R : ¹H-MR spectroscopy differentiates mild cognitive impairment from normal brain ageing. Neuroreport 12: 2315–2317, 2001.

Chantal S Labelle M Bouchard RW : Correlation of regional proton magnetic resonance spectroscopic metabolic changes with cognitive deficits in mild Alzheimer disease. Arch Neurol 59: 955–62, 2002.

Burggren AC Small GW Sabb FW : Specificity of brain activation patterns in people at genetic risk for Alzheimer's disease. AM J Greater Psychiatry 10: 44–51, 2002.

Rombouts S Scheltens P : Functional connectivity in elderly controls and AD patients using resting state fMRI: a pilot study. Cur Alzheimer Res 2: 115–6, 2005.

Kantarci K Jack CR Xu YC : Mild cognitive impairment and Alzheimer's disease: regional diffusivity of water. Radiology 219: 101–107, 2001.

Gomez-Anson B Sanchez-Guerra M Ferrer I : MR imaging findings and radiological-pathologic correlation in a case of postvaccination meningoencephalitis in Alzheimer's disease. Proceedings 43rd Annual Meeting of the ASNR. Toronto 2005, 301.

Fellgiebel A Muller MJ Wille P : Color-coded diffusion-tensor-imaging of posterior cingulate fiber tracts in mild cognitive impairment. Neurobiol Ageing 26: 1193–8, 2005.

Choi SJ Lim KO Monteiro Y : Diffusion tensor imaging of frontal white matter microstructure in early Alzheimer's disease: a preliminary study. J Geriatr Psychiatry Neurol 18: 12–9, 2005.

Boccardi M Laakson MP Bresciani L : The MRI pattern of frontal and temporal brain atrophy in frontotemporal dementia. Neurobiol Ageing 24: 95–103, 2003.

Galton CG Gomez-Anson B Antoun N : Temporal lobe rating scale: application to Alzheimer's disease and fronto-temporal dementia. J Neurol neurosurg Psychiatry 70: 165–173, 2001.

Chan D Fox NC Jenkins R : Rates of global and regional cerebral atrophy in AD and frontotemporal dementias. Neurology 57: 1756–63, 2001.

Catani M Piccirilli M Cherobini A : Axonal injury within language network in primary progressive aphasia. Ann Neurol 53: 242–7, 2003.

Laarson EM Englund E Sjobeck M : MRI with diffusion tensor imaging at 3T in a patient with frontotemporal dementia. Dement Geriatr Cogn Disord 17: 316–9, 2004.

Junque C Ramirez-Ruiz B Tolosa E : Amygdalar and hippocampal MRI reductions in Parkinson's disease with dementia. Movement Disorders 20: 540–544, 2005.

Summerfield C Junque C Tolosa E : Structural brain changes in Parkinson disease with dementia: a voxel-based morphometry study. Arch Neurol 62: 281–285, 2005.

Gomez-Anson B Junque C Tolosa E : Progressive grey matter atrophy in Parkinson's disease with and without dementia: an in vivo quantitative study on MRI (unpublished data).

Ramírez-Ruiz B Martí MJ Tolosa E : Longitudinal evaluation of cerebral morphological changes in Parkinson's disease with and without dementia. J Neurol 2005 (in press).

Summerfield C Gómez-Ansón B Tolosa E : Dementia in Parkinson's disease: A Proton Magnetic Resonance Spectroscopy study. Archives in Neurology 59: 1415–20, 2002.

Tost H Wendt CS Schmitt A : Huntington's disease: phenomenological diversity of a neuropsychiatric condition that chanllenges traditional concepts in neurology and psychiatry. Am J Psychiatry 161: 28–34, 2004.

Huntington's Disease Collaborative Research Group: A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72: 971–983, 1993.

Aylward EH Rosenblatt A Field K : Caudate volume as an outcome measure in clinical trials for Huntington's disease: a pilot study. Brain Research Bulletin 62: 137–141, 2003.

Kassubek J Juengling FD Kioschies T : Topography of cerebral atrophy in early Huntington's disease: a voxel based morphometry MRI study. J Neurol Neurosurg Psychiatry 75: 213.20, 2004.

Sánchez-Pernaute R García-Segura JM Del Barrio Alba A : Clinical correlation of striatal ¹H MRS changes in Huntington's disease. Neurology 53: 806–812, 1999.

Gomez-Tortosa E MacDonald ME Friend JC : Quantitative neuropathological changes in presymptomatic Huntington's disese. Ann Neurol 49: 29–34, 2001.

Gomez-Anson B Alegret M Muñoz E : MR Spectroscopy changes in the frontal lobe occur in presymptomatic Huntington's disease and correlate to oculomotor dysfunction. Proceedings 43rd Annual Meeting of the ASNR. Toronto 2005: 243.

Gomez-Anson B Sainz A Alegret M : Brain Atrophy is Present in Presymptomatic Carriers of Huntington's Disease on MRI and Correlates with Neuropsychological Dysfunction. To be presented at the XXX ESNR Congress, Barcelona 2005.

Rosas HD Liu AK Hersch S : Regional and progressive thinning of the cortical ribbon in Huntington's disease. Neurology 58: 695–701, 2002.

Thieben MJ Duggins AJ Good CD : The distribution of structural neuropathology in preclinical Huntington's disease. Brain 125: 1815–1828, 2002.

Gomez-Anson BM Sainz A Alegret M : Functional MR Imaging in presymptomatic Huntington's disease reveals global hypoactivation with motor and verbal fluency tasks. Proceedings 43rd Annual Meeting of the ASNR. Toronto 2005: 244.

Kantarci K Jack CR : Neuroimaing in Alzheimer disease: an evidence-based review. Neuroimaging Clin N Am 13: 197–209, 2003.

Petrella JR Coleman RE Doraiswamy PM : Neuroimaging and early diagnosis of Alzheimer disease: a look to the future. Radiology 226: 315–36, 2003.