Encefalopatia ipossico-ischemica

Abstract

The term hypoxic-ischaemic encephalopathy, often used to cover the whole spectrum of perinatal brain damage, should be confined to neonatal suffering at term presenting specific physiopathological, clinical and radiological features. Most perinatal brain lesions are secondary to perinatal or post-natal hypoxic-ischaemic injury and can be classified on the basis of the predominant morphological characteristics (table 1). The different locations and morphological expression of brain damage in the premature infant and the neonate born at term reflect the different levels of brain maturation (table 2). These tables summarize the different pathogenetic and anatomopathological features of hypoxic-ischaemic lesions with clinical and radiological references in the premature infant and neonate born at term.