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Abstract

Sixteen lanostane-type triterpeneoids were isolated from the fruiting bodies of wild Ganoderma lucidum and G. multipileum. The new structures 3S,24S,25,26-tetrahydroxy-5α-lanost-8-en-11-one (1) and ganodermanondiol 24,25-acetonide (10) were elucidated by means of spectroscopic data and Mosher's experiments. Lanosta-7,9(11)-dien-3β-ol (9) strongly inhibited α-glucosidase with the IC₅₀ values of 198.8 μM in compared with acarbose (IC₅₀ 712.4 μM).

Keywords

Ganoderma lucidum Ganoderma multipileum Ganodermataceae Lanostane α-Glucosidase

References

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Lanostane-type Triterpenoids from Ganoderma lucidum and G. multipileum Fruiting Bodies

Abstract

Keywords

References

Supplementary Material