Free accessReview articleFirst published online 2018-4
Chemo- and Enantioselective Catalytic Hydrogenation of α,β-Unsaturated Ketones and Aldehydes as a Tool to Introduce Chiral Centers at α- or β-Positions of Ketones
Catalytic enantioselective hydrogenations of acyclic and cyclic α,β-unsaturated ketones and aldehydes are useful protocols for introduction of chiral centers at α- and/or β-positions of ketones especially in process scale reactions, which are reviewed in addition to conjugate and organocatalytic transfer reductions from the literatures since 2000.
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