The biotransformation of daidzein and its diacetate was investigated using cultured plant cells of Phytolacca americana as biocatalysts. Daidzein was glucosylated to the corresponding 7-O-β-D-glucoside. On the other hand, daidzein diacetate was hydrolyzed to daidzein, which was further glucosylated to 7-O-β-D-glucoside with much higher yield in comparison with the biotransformation of daidzein. Daidzein 7-O-β-D-glucoside showed higher inhibitory activity for histamine release from rat peritoneal mast cells than daidzein.
MarottaF, MaoGS, LiuT, ChuiDH, LorenzettiA, XiaoY, MarandolaP. (2006) Anti-inflammatory and neuroprotective effect of a phytoestrogen compound on rat microglia. Annals of the New York Academy of Sciences, 1089, 276–281.
2.
ShimodaK, KubotaN, HamadaM, UesugiD, TanigawaM, HamadaH, HamadaH. (2014) Glycosylation of quercetin with cultured plant cells and cyclodextrin glucanotransferase. Natural Product Communications, 9, 647–648.
3.
ShimodaK, KubotaN, UesugiD, HamadaH. (2014) Glycosylation of artepillin C with cultured plant cells of Phytolacca americana. Natural Product Communications, 9, 683–685.
4.
ShimodaK, KubotaN, UesugiD, FujitakaY, OkadaS, TanigawaM, HamadaH. (2015) Regioselective glycosylation of 3-, 5-, 6-, and 7-hydroxyflavones by cultured plant cells. Natural Product Communications, 10, 923–924.
5.
ShimodaK, KubotaN, HamadaH, HamadaH. (2015) Synthesis of resveratrol glycosides by plant glucosyltransferase and cyclodextrin glucanotransferase and their neuroprotective activity. Natural Product Communications, 10, 995–996.
6.
HamadaH, HamadaH, ShimodaK. (2015) Synthesis of ε-viniferin glycosides by glucosyltransferase from Phytolacca americana and their inhibitory activity on histamine release from rat peritoneal mast cells. Natural Product Communications, 10, 1017–1018.
7.
ShimodaK, KubotaN, UesugiD, TanigawaM, HamadaH. (2016) Hydroxylation and glycosylation of phenylpropanoids by cultured cells of Phytolacca americana. Natural Product Communications, 11, 197–198.
8.
UesugiD, HamadaH, ShimodaK. (2016) Glycosylation of trans-resveratrol by cultured plant cells under illumination of LEDs. Natural Product Communications, 11, 199–200.
9.
ShimodaK, KubotaN, TanigawaM, HamadaH. (2016) Glycosylation of Chrysin by Cultured Cells of Eucalyptus perriniana. Natural Product Communications, 11, 1097–1098.
10.
HirataT, KoyaK, SarfoKJ, ShimodaK, ItoDI, IzumiS, OhtaS, LeeYS. (1999) Glucosylation of benzyl alcohols by the cultured suspension cells of Nicotiana tabacum and Catharanthus roseus. Journal of Molecular Catalysis B: Enzymatic, 6, 67–73.
