Optical Resolution of ( RS )-Denopamine to ( R )-Denopamine β-D-Glucoside by Glucosyltransferase from Phytolacca americana Expressed in Recombinant Escherichia coli
Free accessResearch articleFirst published online August, 2016
Optical Resolution of ( RS )-Denopamine to ( R )-Denopamine β-D-Glucoside by Glucosyltransferase from Phytolacca americana Expressed in Recombinant Escherichia coli
The optical resolution of racemic compounds by stereoselective glucosylation was investigated using plant glucosyltransferase from Phytolacca americana expressed in recombinant Escherichia coli. The glucosyltransferase glucosylated chemoselectively the phenolic hydroxyl group of phenol compounds. The (R)-stereoselective glucosylation of (RS)-denopamine by glucosyltransferase occurred to give (R)-denopamine β-D-glucoside.
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