Carvone has corroborated its versatility as starting material for building blocks synthesis in organic chemistry, being achieved a new chiral lactone. It has been done a study on the antioxidant activity against superoxide of carvone and a chloro derivative that show the potent activity of the natural product (R)-carvone, 1.
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2.
MarcosIS, CastañedaL, BasabeP, DíezD, UronesJG. (2008) Synthesis of sibiricinone A, sibiricinone B and leoheterin. Tetrahedron, 64, 10860–10866
3.
MarcosIS, CastañedaL, BasabeP, DíezD, UronesJG. (2008) Synthetic studies to highly functionalised B ring labdanes. Tetrahedron, 64, 8815–8829.
4.
MarcosIS, EscolaMA, MoroRF, BasabeP, DiezD, SanzF, MollinedoF, de la Iglesia-VicenteJ, SierraBG, UronesJG (2007) Synthesis of novel antitumoral analogues of dysidiolide from ent-halimic acid. Bioorganic Medicinal Chemistry, 15, 5719–5737
5.
MarcosIS, PedreroAB, SexmeroMJ, DiezD, BasabeP, GarcíaN, MoroRF, BroughtonHB, MollinedoF, UronesJG. (2003) Synthesis of bioactive sesterterpenolides from ent-halimic acid. 15-Epi-ent-cladocoran A and B. Journal Organic Chemistry, 68, 7496–7504
6.
MarcosIS, PedreroAB, SexmeroMJ, DiezD, BasabeP, HernándezFA, UronesJG (2003) Synthesis and absolute configuration of three natural ent-halimanolides with biological activity. Tetrahedron Letters, 44, 369–372.
7.
RodillaJM, NevesPP, PombalS, RivesV, TrujillanoR, DiezD. (2016) Hydrotalcite catalysis for the synthesis of new chiral building blocks. Natural Product Research, 26, 486–492.
8.
GhoshAK, XiK (2009) Total synthesis of (-)-platensimycin, a novel antibacterial agent. Journal Organic Chemistry, 74, 1163–1170
9.
ValeevRF, SeleznevaN K, StarikovaZA, Pankrat'evEY, MiftakhoMS. (2010) Chiral building blocks from R-(–)-carvone: N-bromosuccinimide-mediated addition – sceletal rearrangement of (–)-cis-carveol. Mendeleev Communications, 20, 77–79
10.
HagiwaraH. (2013) Carvone as a versatile chiral building block for total syntheses of heterocyclic sesquiterpenoids. Natural Product Communications, 7, 935–948.
11.
TahirI, KhanMR, ShahNAAftabM, (2016) Evaluation of phytochemicals, antioxidant activity and amelioration of pulmonary fibrosis with Phyllanthus emblica leaves. BMC Complementary and Alternative Medicine, 16, 268–284.
12.
YazerskiVA, SpannringP, GatineauD, WoerdeCHM, WieclawskaSM, LutzM, KleijnH, GebbinkRJMK. (2014) Making Fe(BPBP)-catalyzed C–H and C=C oxidations more affordable. Organic and Biomolecular Chemistry Journal, 12, 2062–2070.
13.
MehtaG, ChattopadhyaySK, UmaryeJD. (1999) A new carvone based construction of the ring-A of taxoids, Tetrahedron Letters, 40, 4881–4884.
14.
HuangB, ZhangF, YuG, SongY, WangX, WangM, GongZ, SuR, JiaY. (2016) Gram scale syntheses of (-)-incarvillateine and its analogs. Discovery of potent analgesics for neuropathic pain. Journal of Medicinal Chemistry, 59, 3953–3963.
15.
PacherP, BeckmanJS, LiaudetL (2007) Nitric oxide and peroxynitrite in health and disease. Physiological Reviews, 87, 315–424.
16.
LeeYJ, KimDB, LeeJS, ChoJH, KimBK, ChoiHS, LeeBY, LeeOH (2013) Antioxidant activity and anti-adipogenic effects of wild herbs mainly cultivated in Korea. Molecules, 18, 12937–12950.
17.
NagulendranKR, VelavanS, MaheshR, HazeenaBegum V (2007) In vitro antioxidant activity and total polyphenolic content of Cyperus rotundus rhizomes. European Journal of Chemistry, 4, 440–449.
18.
KassanM, MonteroMJ, SevillaMA. (2010) In vitro antioxidant activity of pravastatin provides vascular protection. European Journal of Pharmacology, 630, 107–111.
