From the roots of Acronychia pedunculata (L.) Miq. (Rutaceae) collected in Taiwan, six known and three new acetophenones have been isolated. The new compounds were named acrophenones D (1), E (2), and F (3). Of the acetophenones isolated in this study, prenylacronylin (4) and acronyculatin D (10) exhibited significant inhibitory activity against 12-O-tetradecanoylphorbol 13-acetate-induced Epstein-Barr virus early antigen activation in Raji cells.
MotohashiN, YamagamiC, TokudaH, KonoshimaT, OkudaY, OkudaM, MukainakaT, NishinoH, SaitoY. (1998) Inhibitory effects of dehydrozingerone and related compounds on 12-O-tetradecanoylphorbol-13-acetate induced Epstein–Barr virus early antigen activation. Cancer Letters, 134, 37–42.
8.
ItoC, ItoigawaM, FurukawaH, RaoKS, EnjoF, BuP, TakayasuJ, TokudaH, NishinoH. (1998) Xanthones as inhibitors of Epstein-Barr virus activation. Cancer Letters, 132, 113–117.
