Phytochemical investigation of the leaves of Trichilia connaroides led to the isolation of a new pregnane, trichilone (1), featuring a 2-methoxycyclopent-2-enone moiety, along with a related known compound, 3β,4α-dihydroxypregnane-16-one (2). The structure of 1 was established on the basis of extensive spectroscopic analysis. Compound 1 showed significant root-growth inhibition activity against Amaranthus. mangostanus with an IC50 value of 23.1 ppm.
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4.
ZhangHP, WuSH, ShenYM, MaYB, WuDG, QiSH, LuoXD. (2003) A pentanotriterpenoid with a novel carbon skeleton and a new pregnane from Trichilia connaroides. Canadian Journal of Chemistry, 81, 253–257.
