A new prenylated isoflavone, pomiferin-4′-O-methyl ether, and a new prenylated chalcone, 2′,4′-dihydroxy-4-methoxy-3′-(2-hydroxy-3-methylbut-3-enyl)chalcone, together with four known flavonoids, were isolated from the leaves of Derris malaccensis. All isolated compounds were evaluated for their cytotoxicity.
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