Morinda citrifolia, has been reported to posses different biological activities and almost all parts of this have been studied phytochemically. However there are few studies on the seeds of fruit. The objective of present study was investigated the effect to Noni Seed Oil (NSO) on serum lipid levels in normolipidemic and hyperlipidemic induced mice. We find that administration of noni oil causes a reduction in total cholesterol and triglycerides levels in both models. However hypolipidemic effect is higher when hyperlipidemia is presented.
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4.
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7.
NayakBS, MarshallJ.R., IsitorG, AdogwaA. (2011) Hypoglycemic and hepatoprotective activity of fermented fruit juice of Morinda citrifolia (noni) in diabetic rats. Evidence-Based Complementary and Alternative Medicine. doi:10.1155/2011/875293; (b) Madaeva Rao US, Subramanian S. (2009) Biochemical evaluation antihyperglycemic and antioxidative effects of Morinda citrifolia extract studied in streptozotocin-induced diabetic rats. Medicinal Chemistry Research, 18, 433-446.
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McKoyM.L.G., ThomasE.A., SimonO.R. (2002) Preliminary investigation of the anti-inflammatory properties of an aqueous extract from Morinda citrifolia (Noni). Pharmacological Society, 45, 76–78; (b) Akihisa T, Matsumoto K, Tokuda H, Yasukawa K, Seino K, Nakamoto K, Kuninaga H, Suzuki T, Kimura Y. (2007) Anti-inflammatory and potential cancer chemopreventive constituents of the fruits of Morinda citrifolia (Noni). Journal of Natural Products, 70, 754-757.
9.
HirazumiA., FurusawaE. (1999) An immunomodulatory polysaccharide- rich substance from the fruit juice of Morinda citrifolia (Noni) with antitumor activity. Phytotherapy Research, 13, 380–387; (b) Hirazumi A, Furusawa E, Chou S C, Hokama Y. (1996) Immunomodulation contributes to the anticancer activity of Morinda citrifolia (noni) fruit juice. Proceedings of the Western Pharmacology Society, 39, 7-9.
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SilvaR.M., SantosF.A., MacielM.A., PintoA.C., RaoV.S.N. (2001) Effect of trans-dehydrocrotonin, a 19-nor-clerodane diterpene from Croton cajucara on experimental hypertrigliceridemia and hypercholesterolaemia induced by Triton WR 1339 (Tyloxapol) in Mice. Planta Medica, 67, 763–765.
