One new cembrane diterpenoid, named sarcolactone A (1), along with five known compounds (2–6) were isolated from the soft coral Sarcophyton infundibuliforme collected from the South China Sea. The structure of sarcolactone A (1) was elucidated by comprehensive analysis of spectral data, especially 2D-NMR spectra (1H-1H COSY, HMBC and NOESY). All the compounds were evaluated for their brine shrimp lethality and antifouling activities.
CarboneM, Nunez-PonsL, CastelluccioF, AvilaC, GavagninM. (2009) Illudalane sesquiterpenoids of the alcyopterosin series from the Antarctic Marine soft coral Alcyonium grandis. Journal of Natural Products, 72, 1357–1360.
2.
JurekJ, ScheuerPJ. (1993) Sesquiterpenoids and norsesquiterpenoids from the soft coral Lemnalia africana. Journal of Natural Products, 56, 508–513.
3.
ZhangCX, LiJ, SuJY, LiangYJ, YangXP, ZhengKC, ZengLM. (2006) Cytotoxic diterpenoids from the soft coral Sarcophyton crassocaule. Journal of Natural Products, 69, 1476–1480.
4.
ZhangCX, YanSJ, ZhangGW, LuWG, SuJY, ZengLM, GuLQ, YangXP, LianYJ. (2005) Cytotoxic diterpenoids from the soft coral Sinularia microclavata. Journal of Natural Products, 68, 1087–1089.
5.
TomonoY, HirotaH, ImaharaY, FusetaniN. (1999) Four new steroids from two octocorals. Journal of Natural Products, 62, 1538–1541.
SawantSS, YoussefDTA, SylvesterPW, WaliV, El SayedKA. (2007) Antiproliferative sesquiterpenes from the Red Sea soft coral Sarcophyton glaucum. Natural Product Communications, 2, 117–119.
8.
VanMC, CuongNX, TuanTA, ChoiEM, KimYH, VanKP. (2007) A new 9,11-secosterol from the Vietnamese sea soft coral, Sarcophyton mililatensis, increases the function of osteoblastic MC3T3-E1 cells. Natural Product Communications, 2, 1095–1100.
9.
GroteD, ShakerKH, SolimanHSM, HegaziMM, SeifertK. (2008) Cembranoid diterpenes from the soft corals Sarcophyton sp. and Sarcophyton glaucum. Natural Product Communications, 3, 1473–1478.
10.
LanWJ, WangSL, LiHJ. (2009) Additional new tetracyclic tetraterpenoid: methyl tortuoate D from soft coral Sarcophyton tortuosum. Natural Product Communications, 4, 1193–1196.
11.
VanderahDJ, RutledgeN, SchmitzFJ, CiereszkoLS. (1978) Marine natural products: cembrene-A and cembrene-C from a soft coral, Nephthea species. Journal of Organic Chemistry, 43, 1614–1616.
12.
RaoZG, DengSZ, WuHM, JiangSK. (1998) Rhabdasterol, a new steroid from the South China Sea marine sponge Rhabdastrella sp. Chemical Journal of Chinese Universities, 19, 406–407.
13.
BowdenBF, CollJC, TapiolasDM. (1987) Studies of Australian soft corals. XXXIII. New cembranoid diterpenes from a Lobophytum species. Australian Journal of Chemistry, 36, 2289–2295.
14.
PoetSE, RaviBN. (1982) Three new diterpenes from a soft coral Nephthea species. Australian Journal of Chemistry, 35, 77–83.
15.
LiH, RuanDL, LiYG. (2004) Separation and identification of squalene in liver oil from Mustelus griseus. Chinese Journal of Marine Drugs, 23, 34–35.
16.
BandurragaMM, FenicalW, DonovanSF, ClardyJ. (1982) Pseudopterolide, an irregular diterpenoid with unusual cytotoxic properties from the Caribbean sea whip Pseudopterogorgia acerosa (Pallas) (Gorgonacea). Journal of the American Chemical Society, 104, 6463–6465.
17.
JiaR, GuoYW, MolloE, GavagninM, CiminoG. (2006) Sarcophytonolides E–H, cembranolides from the Hainan soft coral Sarcophyton latum. Journal of Natural Products, 69, 819–822
18.
LiL, WangCY, ShaoCL, GuoYW, LiGQ, SunXP, HanL, HuangH, GuanHS. (2009) Sarcoglycosides A–C, new O-glycosylglycerol derivatives from the South China Sea soft coral Sarcophyton infundibuliform. Helvetica Chimica Acta, 92, 1495–1502.
19.
SolisPN, WrightCW, AndersonMM, GuptaMP, PhillipsonJD. (1993) A microwell cytotoxicity assay using Artemia salina (brine shrimp). Planta Medica, 59, 250–252.
20.
MeyerBN, FerrigniNR, PutnamJE, JacobsenLB, NicholsDE, McLaughlinJL. (1982) Brine shrimp: a convenient general bioassay for active plant constituents. Planta Medica, 45, 31–34.
21.
HarderT, ThiyagarajanV, QianPY. (2001) Combined effect of cyprid age and lipid content on larval attachment and metamorphosis of Balanus amphitrite Darwin. Biofouling: The Journal of Bioadhesion and Biofilm Research, 17, 257–262.
22.
QiSH, ZhangS, QianPY, XiaoZH, LiMY. (2006) Ten new antifouling briarane diterpenoids from the South China Sea gorgonian Junceella juncea. Tetrahedron, 62, 9123–9130.
