This review provides a panoramic view of Prof. Kurt Hostettmann's contribution to the study of African medicinal plants as documented in over 85 publications with collaborators from about a dozen African countries. Many novel bioactive secondary metabolites were isolated, their structures elucidated by hyphenated HPLC techniques and their biological activity determined.
DomonB, HostettmannK. (1984) New saponins from Phytolacca dodecandra l'Hérit. Helvetica Chimica Acta, 67, 1310–1315.
2.
BergeronC, MarstonA, HakizamunguE, HostettmannK. (1995) Antifungal constituents of Chenopodium procerum. International Journal of Pharmacognosy, 33, 115–119.
3.
CogneA-L, QueirozEF, WolfenderJ-L, MarstonA, MaviS, HostettmannK. (2003) On-line identification of unstable catalpol derivatives from Jamesbrittenia fodina by LC-MS and LC-NMR. Phytochemical Analysis, 14, 67–73.
4.
RathG, TouréA, NiangaM, WolfenderJ-L, HostettmannK. (1995) Characterization of C-glycosylflavones from Dissotis rotundifolia by liquid chromatography - UV diode array detection - tandem mass spectrometry. Chromatographia, 41, 332–342.
5.
QueirozEF, WolfenderJ-L, AtindehouKK, TraoreD, HostettmannK. (2002) On-line identification of the antifungal constituents of Erythrina vogelii by liquid chromatography with tandem mass spectrometry ultraviolet absorbance detection and nuclear magnetic resonance spectrometry combined with liquid chromatographic micro-fractionation. Journal of Chromatography A, 974, 123–134.
6.
CogneA-L, QueirozEF., MarstonA, WolfenderJ-L, MaviS, HostettmannK. (2005) On-line identification of unstable iridoids from Jamesbrittenia fodina by HPLC-MS and HPLC-NMR. Phytochemical Analysis, 16, 429–439.
7.
MaillardM, HostettmannK. (1993) Analysis of saponins in crude plant extracts by thermospray LC-MS. Journal of Chromatography, 647, 137–146.
8.
DorsazAC, HostettmannK. (1986) Further saponins from Phytolacca dodecandra L'Hérit. Helvetica Chimica Acta, 69, 2038–2047.
9.
MaillardM, AdewunmiCO, HostettmannK. (1992) A triterpene glycoside from the fruits of Tetrapleura tetraptera. Phytochemistry, 31, 1321–1323.
10.
FuzzatiN, WolfenderJ-L, HostettmannK, MsonthiJD, MaviS, MolleyresLP. (1996) Isolation of antifungal valepotriates from Valeriana capense and the search for valepotriates in crude Valerianaceae extracts. Phytochemical Analysis, 7, 76–85.
11.
PotteratO, HostettmannK, Stoeckli-EvansH, SaadouM. (1992) Saponins with an unusual secoursene skeleton from Sesamum alatum Thonn. Helvetica Chimica Acta, 75, 833–841.
12.
FerrariJ, TerreauxC, KurtánT, Szikszai-KissA, AntusS, MsonthiJD, HostettmannK. (2003) Isolation and on-line LC/CD analysis of 3,8″-linked biflavonoids from Gnidia involucrata. Helvetica Chimica Acta, 86, 2768–2778.
13.
QueirozEF, WolfenderJ-L, RaoelisonG, HostettmannK. (2003) Determination of the absolute configuration of 6-alkylated α-pyrones from Ravensara crassifolia by LC/NMR. Phytochemical Analysis, 14, 34–39.
14.
BringmannG, SaebW, GodR, SchäfferM, FrançoisG, PetersK, PetersEM, ProkschP, HostettmannK, AkéAssi L. (1998) 5′-O-demethyldioncophylline A, a new antimalarial alkaloid from Triphyophyllum peltatum. Phytochemistry, 49, 1667–1673.
15.
BringmannG, HolenzJ, Aké AssiL, ZhaoC, HostettmannK. (1996) Molluscicidal activity of naphthylisoquinoline alkaloids from Triphyophyllum and Ancistrocladus species. Planta Medica, 62, 556–557.
GunternA, IosetJ-R, QueirozEF, SandorP, FogginCM, HostettmannK. (2003) Heliotropamide, a novel oxopyrrolidine-3-carboxamide from Heliotropium ovalifolium. Journal of Natural Products, 66, 1550–1553.
18.
AhuaKM, IosetJ-R, RansijnA, MauëlJ, MaviS, HostettmannK. (2004) Antileishmanial and antifungal acridone derivatives from the roots of Thamnosma rhodesica. Phytochemistry, 65, 963–968.
19.
QueirozEF, HayA-E, ChaaibF, Van DiemenD, DialloD, HostettmannK. (2006) New and bioactive aromatic compounds from Zanthoxylum zanthoxyloides. Planta Medica, 72, 746–750.
AtindehouKK, QueirozEF, TerreauxC, TraoreD, HostettmannK. (2002) Three new prenylated isoflavonoids from the root bark of Erythrina vogelii. Planta Medica, 68, 181–182.
27.
QueirozEF, AtindehouKK, TerreauxC, AntusS, HostettmannK. (2002) Prenylated isoflavonoids from the root bark of Erythrina vogelii. Journal of Natural Products, 65, 403–406.
MarstonA, ChapuisJC, SordatB, MsonthiJD, HostettmannK. (1986) Anthracenic derivatives from Psorospermum febrifugum and their in vitro cytotoxicities to a human colon carcinoma cell line. Planta Medica, 52, 207–210.
37.
PotteratO, Stoeckli-EvansH, MsonthiJD, HostettmannK. (1987) Two new antifungal naphthoxirene deriatives and their glucosides from Sesamum angolense Welw. Helvetica Chimica Acta, 70, 1551–1157.
38.
GuiletD, GunternA, IosetJ-R, QueirozEF, NdjokoK, FogginC M, HostettmannK. (2003) Absolute configuration of a tetrahydrophenanthrene from Heliotropium ovalifolium by LC-NMR of its Mosher esters. Journal of Natural Products, 66, 17–20.
39.
DécosterdLA, Stoeckli-EvansH, MsonthiJD, HostettmannK. (1987) New antifungal chromenyl ketones and their pentacyclic dimers from Hypericum revolutum Vahl. Helvetica Chimica Acta, 70, 1694–1702.
DécosterdLA, Stoeckli-EvansH, ChapuisJC, MsonthiJD, SordatB, HostettmannK. (1989) New hyperforin derivatives from Hypericum revolutum Vahl. with growth-inhibitory activity against a human colon carcinoma cell line. Helvetica Chimica Acta, 72, 464–471.
45.
QueirozEF, KuhlC, TerreauxC, MaviS, HostettmannK. (2003) New dihydroalkylhexenones from Lannea edulis. Journal of Natural Products, 66, 578–580.
PotteratO, MsonthiJD, HostettmannK. (1988) Four iridoid glucosides and a phenylpropanoid glycoside from Sesamum angolense. Phytochemistry, 27, 2677–2679.
GaroE, MaillardM, HostettmannK, Stoeckli-EvansH, MaviS. (1997) Absolute configuration of a diterpene lactone from Parinari capensis. Helvetica Chimica Acta, 80, 538–544.
53.
ZhaoW, WolfenderJ-L, MaviS, HostettmannK. (1998) Diterpenes and sterols from Neoboutonia melleri. Phytochemistry, 48, 1173–1177.
54.
SchallerF, WolfenderJ-L, HostettmannK. (2001) New antifungal ‘quinone methide’ diterpenes from Bobgunnia madagascariensis and study of their interconversion by LC/NMR. Helvetica Chimica Acta, 84, 222–229.
SuterR, TannerM, BorelCH, HostettmannK, FreyvogelTA. (1986) Laboratory and field trials at Ifakara (Kilombero District, Tanzania) on the plant molluscicide Swartzia madagascariensis. Acta Tropica, 43, 69–83.
MaillardM, AdewunmiCO, HostettmannK. (1989) New triterpenoid N-acetylglycosides with molluscicidal activity from Tetrapleura tetraptera Taub. Helvetica Chimica Acta, 72, 668–674.
67.
ToyotaM, MsonthiJD, HostettmannK. (1990) A molluscicidal and antifungal triterpenoid saponin from the roots of Clerodendrum wildii. Phytochemistry, 29, 2849–2851.
HayA-E, IosetJ-R, AhuaKM, DialloD, BrunR, HostettmannK. (2007) Limonoid orthoacetates and antiprotozoal compounds from the roots of Pseudocedrela kotschyi. Journal of Natural Products, 70, 9–13.
