Three known cycloartane-type glycosides were isolated from the roots of two different species of Astragalus, A. glycyphyllos, A. sempervirens. The identification of these compounds were mainly achieved by 2D NMR spectroscopic techniques and FAB-MS. The results of our studies confirm that triterpene saponins from the cycloartane-type skeleton might be chemotaxonomically significant to the genus Astragalus.
ElengaPA, NikolovSt, PanovaD. (1986) Triterpene glycosides and sterols from Astragalus glycyphyllos L. Pharmazie, 41, 300.
2.
(a) ElengaPA, NikolovSt, PanovaD. (1987) Triterpene glycosides from Astragalus glycyphyllos L. A new natural compound of the overgrowing parts of A. glycyphyllos L. Pharmazie, 42, 422–423
3.
(b) ElengaPA, NikolovSt, TopalovaI, PanovaD. (1987) Investigation of the overground parts of Astragalus glycyphyllos L. for glycyrrhetic acid content. F.E.C.S. Third International Conference on Chemistry and Biotechnology of Biologically Active Natural Products [Proceedings], meeting date 1985, publisher: VCH, Weinheim, Fed. Rep. Ger., 4, 281–285.
4.
NikolovSt, ElengaP, PanovaD. (1990) Triterpene saponins from Astragalus glycyphyllos L. Farmatsiya, 40, 12–15.
5.
IsaevMI, GorovitsMB, GorovitsT T, AbdullaevND, AbubakirovNK. (1983) Astragalus triterpenoid glycosides and their genins. VIII. Askendoside C from Astragalus taschkendicus.Khimiya Prirodynkh Soedinenii, 2, 173–180.
6.
IsaevM I. (1995) Triterpene glycosides of Astragalus and their genins. LII. Askendoside F from Astragalus taschkendicus.Khimiya Prirodynkh Soedinenii, 6, 820–823.
7.
BedirE, ÇalişI, AquinoR, PiacenteS, PizzaC. (1999) Trojanoside H: a cycloartane-type glycoside from the aerial parts of Astragalus trojanus. Phytochemistry, 51, 1017–1020.
8.
(a) CarmichaelJ, DeGraffWG, GazdarAF, MinnaJD, MitchellJB. (1987) Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing. Cancer Research, 47, 936–942
9.
(b) Quetin-LeclercqJ, EliasR, BalansardG, BassleerR, AngenotL. (1992) Cytotoxic activity of some triterpenoid saponins. Planta Medica, 58, 279–281.
10.
(a) Li-XianG, Xiano-BingH, Yu-QunC. (1986) AstrasieversianinsIX, XI andXV, cycloartane derived saponins from Astragalus sieversianus.Phytochemistry, 25, 1437–1441
11.
(b) Li-Xian G, Xiano-BingH, Yu-QunC. (1986) The structures of thirteen astrasie-versianins from Astragalus sieversianus.Phytochemistry, 25, 2389–2393
(h) ÇalişI, YusufogluH, ZerbeO, SticherO. (1999) Cephalotoside A: a tridesmosidic cycloartane type glycoside from Astragalus cephalotes var. brevicalyx.Phytochemistry, 50, 843–847
18.
(i) BedirE, ÇalişI, AquinoR, PiacenteS, PizzaC. (1999) Secondary metabolites from the roots of Astragalus trojanus.Journal of Natural Products, 62, 563–568
19.
(j) RadwanMM, El-SebakhyNA, AsaadAM, ToaimaSM, KingstonDGI. (2004) Kahiricosides II-V, cycloartane glycosides from an Egyptian collection of Astragalus kahiricus.Phytochemistry, 65, 2909–2913
20.
(k) ÖzipekM, DönmezA A, ÇalişI, BrunR, RüediP, TasdemirD. (2005) Leishmanicidal cycloartane-type triterpene glycosides from Astragalus oleifolius.Phytochemistry, 66, 1168–1173
21.
(1) ÇalişI, KoyunoğrluS, YeşiladaA, BrunR, RüediP, TaşdemirD. (2006) Antitrypanosomal cycloartane glycosides from Astragalus baibutensis.Chemistry and Biodiversity, 3, 923–929