The essential oil from the leaves of Phyllanthus salviaefolius H. B. K. (Euphorbiaceae) collected in February 2007 at Mucurubá (Mérida State) was analyzed by GC/MS. The yield of oil extracted by hydrodistillation was 0.005%. Sixteen components were identified, which represent 94.6% of the oil. Phytol (21.5%), β-citronellol (17.7%), trans-geraniol (13.5%), cis-3-hexenol (12.6%) and 1-hexanol (11.3%) were the most abundant components.
HuangY, ChenC, OuJ. (1992) Isolintetralin: a new lignan from Phyllanthus niruri. Planta Medica, 58, 473–474.
6.
TanakaR, MatsunagaS. (1988) Triterpene dienols and other constituents from the bark of Phyllanthus flexuosus. Phytochemistry, 27, 2273–77.
7.
SantosA, NieroR, FilhoV, YunesR, PizzolattiM, MonacheF, CalixtoJ. (1995) Antinociceptive of steroids isolated from Phyllanthus corcovadensis in mice. Planta Medica, 61, 329–332.
8.
GutiérrezY, MirandaM, BarrioG, VaronaT, MayoralJ. (2000) Evaluación farmacognóstica y fitoquímica preliminar de Phyllanthus rebicularis H. B. K. Revista Cubana de Farmacia, 34, 56–62.
9.
CalixtoJ, SantosA, Cechinel FilhoV, YunesR. (1998) A review of the plants of the Phyllanthus: their chemistry, pharmacology, and therapeutic potential. Medicinal Research Reviews, 18, 225–258.
10.
BagalkotkarG, SagineeduS, SaadM, StanslasJ. (2006) Phytochemicals from Phyllanthus niruri Linn. and their pharmacological properties: a review. Journal of Pharmacy and Pharmacology, 58, 1559–1570.
HuangR, HuangY, OuJ, ChenC, HsuF, ChangC. (2003) Screening of 25 compounds isolated from Phyllanthus species for anti-human hepatitis B virus in vitro. Phytotherapy Research, 17, 449–53.
14.
LamW, LeungK, Tik-WanL, Ming-YuenL, Lik-YuenC, FungK, Eng-ChoonO, Miu-YeeW. (2006) Antiviral effect of Phyllanthus nanus ethanolic extract against hepatitis B virus (HBV) by expression microarray analysis. Journal of Cellular Biochemistry, 97, 795–812.
15.
YangC, Hua- ChengH, LinT, ChiangL, LinC. (2007) The in vitro activity of geraniin and 1,3,4,6-tetra-O-galloyl-β-D-glucose isolated from Phyllanthus urinaria against herpes simples virus type 1 and type 2 infection. Journal of Ethnopharmacology, 110, 555–558.
16.
HoughtonP, WoldemariamT, SheaS, ThyagarajanS. (1996) Two scurinega-type akaloids from Phyllanthus amarus. Phytochemistry, 43, 715–717.
17.
CalderónA, ValuaF, CastroA, FélixL. (2005) Determinación de compuestos orgánicos de Phyllanthus niruri L. “Chanca Piedra”, actividad antibacteriana y antiviral. V Congreso Mundial de Medicina Tradicional, Lima, Perú. Available at: www.medicina.usmp.edu.pe/congresomundial/000data/temlib.htm-256k-
18.
KumaranA, KarunakaranR. (2007) In vitro antioxidant activities of methanol extracts of five Phyllanthus species from India. LWT - Food Science and Technology, 40, 344–352.
19.
VareschiV. (1970). Flora de los Paramos de Venezuela. Universidad de los Andes. Ediciones del Rectorado, Mérida-Venezuela.
20.
UnanderD, WebsterG, BlumbergB. (1991) Uses and bioassays in Phyllanthus (Euphorbiaceae): a compilation II. The subgenus Phyllanthus. Journal of Ethnopharmacology, 34, 97–133.
JirovetzL, BuchbauerG, SchweigerT, DenkovaZ, SlavchevA, StoyanovaA, SchmidtE, GeisslerM. (2007) Chemical composition, olfactory evaluation and antimicrobial activities of Jasminum grandiflorum L. absolute from India. Natural Product Communications, 2, 407–412.
23.
GulecC, YayliN, YesilgilP, TerziogluS, YayliN. (2007) Chemical composition and antimicrobial activities of the essential oil from the flowers of Delphinium formosum. Asian Journal of Chemistry, 19, 4069–4074.
24.
SetzerW, SchmidtJ, EiterL, HaberW. (2005) The leaf oil composition of Zanthoxylum fagara (L.) Sarg. from Monteverde, Costa Rica, and its biological activities. Journal of Essential Oil Research, 17, 333–335.
25.
De SousaD, GoncalvesJ, QuintansL, CruzJ, AraujoD, de AlmeidaR. (2006) Study of anticonvulsant effect of citronellol, a monoterpene alcohol, in rodents. Neuroscience Letters, 401, 231–235;
26.
O'NeillP, PosnerG. (2004) A medicinal chemistry perspective on artemisinin and related endoperoxides. Journal of Medicinal Chemistry, 47, 2945–2964.
SandraP, BicchiC. (1987) Capillary gas chromatography in essential oil analysis. Huethig, Heidelberg.
29.
AdamsR. (1995) Identification of essential oils components by gas chromatography/mass spectroscopy. Allured Publishing Corporation, Carol Stream IL, USA.
30.
DaviesN. (1990) Gas chromatographic retention indices of monoterpenes and sesquiterpenes on methyl silicone and Carbowax 20 M. phases. Journal of Chromatography A, 503, 1–24.
