The essential oil of C. oblongifolius Roxb. stem bark was obtained by hydrodistillation. Chemical analysis by GC-MS identified 29 compounds. Terpinen-4-ol (17.8%) was a major component, together with α-guaiene (7.9%), E-caryophyllene (7.0%), myrcene (6.7%), (+)-cyclosativene (5.1%), sabinene (4.8%), aciphyllene (4.7%), pogostol (4.6%), γ-terpinene (3.4%), α-muurolol (3.2%) and germecrene D (3.2%). The essential oil exhibited antibacterial activity against Propionibacterium acnes ATCC 6919 with an MIC of 0.125%, v/v.
ChuakulW, SaralampP, PaonilW, TemsiririrkkulR, ClaytonT. (1997) Medicinal plants in Thailand, vol. II. Amarin Printing and Publishing Co. Ltd., Bangkok, Thailand, 85.
2.
PicheansoonthonC, JirawongW. (2013) Handbook of Thai traditional Medicine: Book 5. Amarin Printing and Publishing, Co. Ltd., Bangkok, Thailand, 22–25.
3.
RoengsumranS, PornpakakulS, MuangsinN, SangvanichP, NhujakT, SingtothongP, ChaichitN, PuthongS, PetsomA. (2004) New halimane diterpenoids from Croton oblongifolius. Planta Medica, 70, 87–89;
4.
Yongsa-adW, NgamrojanavanichN, MahidolC, RuchirawatS, PrawatH, KittakoopP. (2007) Diterpenoids from the roots of Croton oblongifolius. Planta Medica, 73, 1491–1494;
5.
TakeshigeY, KawakamiS, MatsunamiK, OtsukaH, LhieochaiphantD, LhieochaiphantS. (2012) Oblongionosides A-F, megastigmane glycosides from the leaves of Croton oblongifolius Roxburgh. Phytochemistry, 80, 132–136.
6.
CraveiroAA, AndradeCHS, MatosFJA, AlencarJW, DantasTNC. (1980) Fixed and volatile constituents of Croton A.F.F. nepetifolius. Journal of Natural Products, 26, 756–757;
7.
SetzerWN, StokesSL, BansalA, HaberWA, CaffreyCR, HansellE, MckerowJH. (2007) Chemical composition and cruzain inhibitory activity of Croton draco bark essential oil from Monteverde, Costa Rica. Natural Product Communications, 2, 685–689;
8.
SuárezAI, OropezaM, VásquezL, TillettS, CompagnoneS. (2011) Chemical composition of the essential oil of Croton gossypiifolius from Venezuela. Natural Product Communications, 6, 97–99;
9.
TurielNA, RibeiroAF, CarvalhoEE, DomingosVD, LucasFC, CarreiraLM, AndradeEH, MaiaJG. (2013) Essential oils composition of Croton species from the Amazon. Natural Product Communications, 8, 1471–1472;
10.
RabehajaDJ, IhandriharisonH, RamanoelinaPA, BenjaR, Ratsimamanga-UrvergS, BighelliA, CasanovaJ, TomiF. (2014) Chemical composition of the essential oil from Croton kimosorum, an endemic species to Madagascar. Natural Product Communications, 8, 129–132;
11.
JoshiRK. (2014) Chemical composition of the essential oil of Croton bonplandianus from India. Natural Product Communications, 9, 269–270;
12.
SylvestreM, PichetteA, LongtinA, NagauF, LegaultJ. (2006) Essential oil analysis and anticancer activity of leaf essential oil of Croton flavens L. from Guadeloupe. Journal of Ethnopharmacology, 103, 99–102;
13.
AzevedoMM, ChavesFC, AlmeidaCA, BizzoHR, DuarteRS, Campos-TakakiGM, AlvianoCS, AlvianoDS. (2013) Antioxidant and antimicrobial activities of 7-hydroxy-calamene rich essential oil from Croton cajucara Benth. Molecule, 18, 1128–1137;
14.
TarikuY, HymeteA, HailuA, RohloffJ. (2010) Constituents, antileishmanial activity and toxicity profile of volatile oil from berries of Croton macrostachyus. Natural Product Communications, 5, 975–980;
15.
NadiGM, FelippiR, DalbóS, Siqueira-JuniorJM, ArrudaDC, Delle MonacheF, TimbolaAK, PizzolattiMG, CklessK, Ribeiro-do-ValleRM. (2003) Anti-inflammatory and antioxidant effects of Croton celtidifolius bark. Phytomedicine, 10, 176–184.
16.
JappeU (2003) Pathological mechanisms of acne with special emphasis on Propionibacterium acnes a related therapy. Acta Dermato-Vereneologica, 83, 241–248.
17.
HammerKA. (2015) Treatment of acne with tea tree oil (Melaleuca) products: a review of efficacy, tolerability, and potential modes of action. International Journal of Antimicrobial Agents, 45, 106–110.
18.
VundaSL, SauterIP, CibulskiSP, RoehePM, BordignonSA, RottMB, ApelMA, von PoserGL. (2012) Chemical composition and amoebicidal activity of Croton pallidulus, Croton ericoides and Croton isabellii (Euphorbiaceae) essential oils, Parasitology Research, 111, 961–966.
19.
RamanA, WeirU, BloomfieldSF. (1995) Antimicrobial effects of tea-tree oil and its major components on Staphylococcus aureus, Staph. epidermidis and Propionibacterium acnes. Letters in Applied Microbiology, 21, 242–245.
20.
AdamRP. (1995) Identification of essential oil components by gas chromatography/ quadrupole mass spectroscopy. Allured Publishing Corporation. Carol Stream IL, USA;
21.
DaviesNW. (1990) Gas chromatographic retention indices of monoterpenes and sesquiterpenes on methyl silicone and Carbowax 20M phases. Journal of Chomatography, 503, 1–24.
22.
CarsonCF, RileyTV. (1994) Susceptibility of Propionibacterium acnes to the essential oil of Melaleuca alternifolia. Letters in Applied Microbiology, 19, 24–25;
23.
SahinF, KaramanI, GüllüceM, OğütçüH, SengülM, AdigüzelA, OztürkS, KotanR. (2003) Evaluation of antimicrobial activities of Satureja hortensis L. Journal of Ethnopharmacology, 87, 61–65.