Abstract
Background:
Glucose is vital for biological processes, requiring blood sugar levels to be maintained between 3.88 and 6.1 mmol/L, especially during fasting. Elevated levels signal diabetes, a global concern affecting 537 million people, necessitating effective glucose-monitoring devices.
Method:
Enzyme-based sensors, though selective, are sensitive to environmental factors. Nonenzymatic sensors, especially those with nanoparticles, offer stability, high surface area, and cost-effectiveness. Existing literature supports their immediate glucose oxidation, showcasing exceptional sensitivity.
Results:
This review details nonenzymatic sensors, highlighting materials, detection limits, and the promise of nanoparticle-based designs, which exhibit enhanced sensitivity and selectivity in glucose detection.
Conclusion:
Nanoparticle-based sensors, as reviewed, show potential for glucose monitoring, overcoming enzyme-based limitations. The conclusion suggests future directions for advancing these sensors, emphasizing ongoing innovation in this critical research area.
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